Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR. (Q34657661)

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English	Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.	scientific article

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8 January 2020

Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR (English)

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8 January 2020

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8 January 2020

Linda A Sherman

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8 January 2020

Steven Rosenberg

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Steven A Rosenberg

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8 January 2020

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Zhili Zheng

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8 January 2020

Regina Bray

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8 January 2020

Yangbing Zhao

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8 January 2020

Richard A Morgan

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1 November 2005

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8 January 2020

Journal of Immunology

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8 January 2020

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8 January 2020

5799-5808

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8 January 2020

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions

1 reference

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7 July 2018

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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7 July 2018

Primary antitumor immune response mediated by CD4+ T cells

1 reference

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7 July 2018

Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines

1 reference

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Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor.

1 reference

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7 July 2018

p53 as an immunotherapeutic target in head and neck cancer.

1 reference

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7 July 2018

Genetic modification of T lymphocytes for adoptive immunotherapy

1 reference

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7 July 2018

p53: 25 years after its discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Recombinant antibodies with MHC‐restricted, peptide‐specific, T‐cell receptor‐like specificity: new tools to study antigen presentation and TCR–peptide–MHC interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Adoptive-cell-transfer therapy for the treatment of patients with cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

P53(110-124)-specific human CD4+ T-helper cells enhance in vitro generation and antitumor function of tumor-reactive CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Adoptive therapy with CD8(+) T cells: it may get by with a little help from its friends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

T-cell-receptor gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein-Barr virus potential through both culture-dependent and selection process-dependent mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Generation of T cells specific for the wild-type sequence p53(264-272) peptide in cancer patients: implications for immunoselection of epitope loss variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

High steady-state levels of p53 are not a prerequisite for tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

p53: a potential target antigen for immunotherapy of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Strategies for immunotherapy of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Retrovirus-mediated gene transfer in primary T lymphocytes: influence of the transduction/selection process and of ex vivo expansion on the T cell receptor beta chain hypervariable region repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Targeting of human p53-overexpressing tumor cells by an HLA A*0201-restricted murine T-cell receptor expressed in Jurkat T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

CD4 T cells and their role in antitumor immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

The central role of CD4(+) T cells in the antitumor immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Accumulation of the p53 protein allows recognition by human CTL of a wild-type p53 epitope presented by breast carcinomas and melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

The use of transgenic mice to generate high affinity p53 specific cytolytic T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

A Simple and Reliable Method for Screening Retroviral Producer Clones Without Selectable Markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Targeting p53 as a general tumor antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

p53, a potential target for tumor-directed T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Lysine 271 in the transmembrane domain of the T-cell antigen receptor beta chain is necessary for its assembly with the CD3 complex but not for alpha/beta dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

The p53 tumour suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

7 July 2018

Immune responses to p53 in patients with cancer: enrichment in tetramer+ p53 peptide-specific T cells and regulatory T cells at tumor sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Vaccination with p53-peptide-pulsed dendritic cells, of patients with advanced breast cancer: report from a phase I study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Frequencies of tetramer+ T cells specific for the wild-type sequence p53(264-272) peptide in the circulation of patients with head and neck cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Induction of cytotoxic T lymphocyte and antibody responses to enhanced green fluorescent protein following transplantation of transduced CD34(+) hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients

1 reference

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26 October 2018

In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild-type p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1473968

26 October 2018

Versatile retroviral vectors for potential use in gene therapy

1 reference

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26 October 2018

Focus on the p53 gene and cancer: advances in TP53 mutation research

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC class I-restricted recognition of a melanoma antigen by a human CD4+ tumor infiltrating lymphocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy through TCR gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of p53-specific immune responses in colorectal cancer patients receiving a recombinant ALVAC-p53 candidate vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The physiological role of cytotoxic CD4(+) T-cells: the holy grail?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue culture studies on pleural effusions from breast carcinoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-specific cytolysis by lymphocytes infiltrating human melanomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53 immunostaining in melanocytic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of p53 is a late event in the development of malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 expression in cutaneous malignant melanoma: an immunohistochemical study of 87 cases of primary, recurrent, and metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary proliferative T cell response to wild-type p53 protein in patients with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent mutations of the p53 gene in cutaneous melanoma of the nodular type

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD4+ T cell responses in antitumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: MHC class II-restricted killing in vivo during viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CD4(+) CTLs ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16237072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.4049/JIMMUNOL.175.9.5799

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8 January 2020

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8 January 2020

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8 January 2020

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