ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining (Q34582166)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20647759%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining (English)

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8 February 2020

5

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8 February 2020

R Scott Williams

4

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Elias A Rahal

object named as

Elias A Rahal

1

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author name string

Leigh A Henricksen

2

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8 February 2020

Yuling Li

3

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8 February 2020

Kathleen Dixon

6

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8 February 2020

publication date

12 July 2010

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8 February 2020

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8 February 2020

volume

9

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8 February 2020

issue

14

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8 February 2020

page(s)

2866-2877

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describes a project that uses

8 February 2020

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3040963/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

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Role of mammalian Mre11 in classical and alternative nonhomologous end joining

7 July 2018

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Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

7 July 2018

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Corrected structure of mirin, a small-molecule inhibitor of the Mre11-Rad50-Nbs1 complex

7 July 2018

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

7 July 2018

1 reference

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ATM mediates repression of DNA end-degradation in an ATP-dependent manner

7 July 2018

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A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex

7 July 2018

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Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.

7 July 2018

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Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

7 July 2018

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Distinctive differences in DNA double-strand break repair between normal urothelial and urothelial carcinoma cells

7 July 2018

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Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

7 July 2018

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IgH class switching and translocations use a robust non-classical end-joining pathway

7 July 2018

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Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

7 July 2018

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Systematic Discovery of In Vivo Phosphorylation Networks

7 July 2018

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Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining

7 July 2018

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Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination

7 July 2018

1 reference

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ATM activation and DNA damage response

7 July 2018

1 reference

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Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement

7 July 2018

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Signaling networks controlled by the MRN complex and MDC1 during early DNA damage responses

7 July 2018

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Abnormal DNA end-joining activity in human head and neck cancer.

7 July 2018

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A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair

7 July 2018

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7 July 2018

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ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

7 July 2018

1 reference

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Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

7 July 2018

1 reference

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DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining

7 July 2018

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Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

7 July 2018

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Cellular machineries for chromosomal DNA repair.

7 July 2018

1 reference

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Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

7 July 2018

1 reference

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Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences

7 July 2018

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The MRN complex: coordinating and mediating the response to broken chromosomes

7 July 2018

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Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures.

7 July 2018

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Neocarzinostatin induces Mre11 phosphorylation and focus formation through an ATM- and NBS1-dependent mechanism

7 July 2018

1 reference

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The BLM helicase is necessary for normal DNA double-strand break repair.

7 July 2018

1 reference

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Chromosomal stability and the DNA double-stranded break connection

7 July 2018

1 reference

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Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts.

7 July 2018

1 reference

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DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

A mechanistic basis for Mre11-directed DNA joining at microhomologies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

In situ visualization of DNA double-strand break repair in human fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040963

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.9.14.12363

Rejoining of DNA double-strand breaks in vitro by single-strand annealing

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.9.14.12363

Rag mutations reveal robust alternative end joining

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.4161%2FCC.9.14.12363

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/20647759

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.9.14.12363

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20647759%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20647759%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

20647759

1 reference