The heme activator protein Hap1 represses transcription by a heme-independent mechanism in Saccharomyces cerevisiae. (Q34572495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654089%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

The heme activator protein Hap1 represses transcription by a heme-independent mechanism in Saccharomyces cerevisiae (English)

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7 January 2020

main subject

Saccharomyces cerevisiae

1 reference

5

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7 January 2020

author name string

Thomas Hon

1

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7 January 2020

Hee Chul Lee

2

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7 January 2020

Zhanzhi Hu

3

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7 January 2020

Vishwanath R Iyer

4

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7 January 2020

language of work or name

English

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publication date

16 January 2005

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7 January 2020

number of pages

10

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inferred from page(s)

published in

Genetics

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7 January 2020

volume

169

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7 January 2020

issue

3

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7 January 2020

page(s)

1343-1352

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Global role of TATA box-binding protein recruitment to promoters in mediating gene expression profiles

7 January 2020

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7 July 2018

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Recruitment of Tup1-Ssn6 by yeast hypoxic genes and chromatin-independent exclusion of TATA binding protein

7 July 2018

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Synergistic repression of anaerobic genes by Mot3 and Rox1 in Saccharomyces cerevisiae

7 July 2018

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7 July 2018

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Structural environment dictates the biological significance of heme-responsive motifs and the role of Hsp90 in the activation of the heme activator protein Hap1

7 July 2018

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7 July 2018

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Evidence that Swi/Snf directly represses transcription in S. cerevisiae

7 July 2018

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Molecular chaperones in the cytosol: from nascent chain to folded protein

7 July 2018

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The Hsp70-Ydj1 molecular chaperone represses the activity of the heme activator protein Hap1 in the absence of heme

7 July 2018

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Molecular mechanism of heme signaling in yeast: the transcriptional activator Hap1 serves as the key mediator.

7 July 2018

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Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

7 July 2018

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Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation

7 July 2018

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RAP, RAP, open up! New wrinkles for RAP1 in yeast

7 July 2018

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Fusions with histone H3 result in highly specific alteration of gene expression

7 July 2018

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A new class of repression modules is critical for heme regulation of the yeast transcriptional activator Hap1.

7 July 2018

1 reference

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Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein

7 July 2018

1 reference

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Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1.

7 July 2018

1 reference

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Flavohemoglobin expression and function in Saccharomyces cerevisiae. No relationship with respiration and complex response to oxidative stress

7 July 2018

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The C6 zinc cluster dictates asymmetric binding by HAP1.

7 July 2018

1 reference

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Function and expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in the oxidative stress response

7 July 2018

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Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo

7 July 2018

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Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1.

7 July 2018

1 reference

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HAP1 is nuclear but is bound to a cellular factor in the absence of heme

7 July 2018

1 reference

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A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.

7 July 2018

1 reference

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Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1

7 July 2018

1 reference

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The yeast activator HAP1--a GAL4 family member--binds DNA in a directly repeated orientation

7 July 2018

1 reference

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Multiple elements and auto-repression regulate Rox1, a repressor of hypoxic genes in Saccharomyces cerevisiae.

7 July 2018

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Evidence for translational regulation of the activator of general amino acid control in yeast

7 July 2018

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ROX1 encodes a heme-induced repression factor regulating ANB1 and CYC7 of Saccharomyces cerevisiae

7 July 2018

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Yeast HAP1 activator binds to two upstream activation sites of different sequence

7 July 2018

1 reference

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CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. I. Overall organization of the protein sequence displays several novel structural domains

7 July 2018

1 reference

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Co-ordinate control of synthesis of mitochondrial and non-mitochondrial hemoproteins: a binding site for the HAP1 (CYP1) protein in the UAS region of the yeast catalase T gene (CTT1).

7 July 2018

1 reference

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Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer

7 July 2018

1 reference

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Functional dissection and sequence of yeast HAP1 activator

7 July 2018

1 reference

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Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1(HAP1) activator binds to the CYB2 upstream activation site UAS1-B2

7 July 2018

1 reference

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Joints in the regulatory lattice: composite regulation by steroid receptor-AP1 complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1449556

Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1449556

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1449556

The molecular chaperone Hsp90 mediates heme activation of the yeast transcriptional activator Hap1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1449556

Regulatory elements that control transcription activation and unsaturated fatty acid-mediated repression of the Saccharomyces cerevisiae OLE1 gene

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1449556

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

27 October 2018

1 reference

12 December 2020

N-terminal deletions of a mitochondrial signal sequence in yeast. Targeting information of delta-aminolevulinate synthase is encoded in non-overlapping regions

1 reference

12 December 2020

Mutations that alter transcriptional activation but not DNA binding in the zinc finger of yeast activator HAPI

1 reference

12 December 2020

CYP1 (HAP1) is a determinant effector of alternative expression of heme-dependent transcription in yeast

1 reference

12 December 2020

HAP1 positive control mutants specific for one of two binding sites

1 reference

12 December 2020

Functional analysis of the zinc cluster domain of the CYP1 (HAP1) complex regulator in heme-sufficient and heme-deficient yeast cells

1 reference

12 December 2020

Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae

1 reference

12 December 2020

Multiple domains mediate heme control of the yeast activator HAP1

1 reference

12 December 2020

Functional analysis of heme regulatory elements of the transcriptional activator Hap1

1 reference

12 December 2020

Transcript analysis of 203 novel genes from Saccharomyces cerevisiae in hap1 and rox1 mutant backgrounds

1 reference

12 December 2020

The yeast heme-responsive transcriptional activator Hap1 is a preexisting dimer in the absence of heme

1 reference

12 December 2020

Regulation of hypoxic gene expression in yeast

1 reference

12 December 2020

Heme regulates SOD2 transcription by activation and repression in Saccharomyces cerevisiae

1 reference

12 December 2020

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1 reference

12 December 2020

10.1534/GENETICS.104.037143

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654089%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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7 January 2020

PubMed publication ID

15654089

1 reference