Short telomeres, even in the presence of telomerase, limit tissue renewal capacity (Q34563497)

3 August 2017

title

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity (English)

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3 August 2017

7

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3 August 2017

Margaret A Strong

3

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Mary Armanios

2

object named as

Mary Armanios

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3 August 2017

Ling-Yang Hao

1

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3 August 2017

Baktiar Karim

4

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3 August 2017

David M Feldser

5

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3 August 2017

David Huso

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3 August 2017

language of work or name

English

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publication date

1 December 2005

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3 August 2017

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3 August 2017

volume

123

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3 August 2017

issue

6

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3 August 2017

page(s)

1121-1131

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Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

3 August 2017

cites work

1 reference

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https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.

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Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia

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Telomeres shorten during ageing of human fibroblasts

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Essential role of mouse telomerase in highly proliferative organs

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11 October 2022

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Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Haploinsufficiency of mTR results in defects in telomere elongation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Regulation of telomerase by telomeric proteins

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11 October 2022

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Functionally interacting telomerase RNAs in the yeast telomerase complex

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Telomerase activity in hematopoietic cells is associated with self-renewal potential

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomere length regulation

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11 October 2022

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Dyskeratosis congenita in all its forms

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Association between aplastic anaemia and mutations in telomerase RNA

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Reverse transcriptase motifs in the catalytic subunit of telomerase

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Protection of mammalian telomeres

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Functional characterization of telomerase RNA variants found in patients with hematologic disorders

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11 October 2022

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Unusual complications after bone marrow transplantation for dyskeratosis congenita

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Fatal interstitial pulmonary disease in a patient with dyskeratosis congenita after allogeneic bone marrow transplantation

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Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome

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Erosion of the telomeric single-strand overhang at replicative senescence

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11 October 2022

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Mammalian telomeres end in a large duplex loop

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Association between telomere length in blood and mortality in people aged 60 years or older

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

The relative lengths of individual telomeres are defined in the zygote and strictly maintained during life

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Mutated PI 3-kinases: cancer targets on a silver platter.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Heterozygous telomerase RNA mutations found in dyskeratosis congenita and aplastic anemia reduce telomerase activity via haploinsufficiency

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Wild-derived inbred mouse strains have short telomeres

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Obesity, cigarette smoking, and telomere length in women

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomere states and cell fates

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomere dysfunction triggers developmentally regulated germ cell apoptosis.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomeres in T and B cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomerase maintains telomere structure in normal human cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Phosphorylation of H2AX at short telomeres in T cells and fibroblasts

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Short telomeres induce a DNA damage response in Saccharomyces cerevisiae

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Dyskeratosis congenita: telomerase, telomeres and anticipation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

G-strand overhangs on telomeres in telomerase-deficient mouse cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

p53 mutant mice that display early ageing-associated phenotypes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.11.020

Identifiers

DOI

10.1016/J.CELL.2005.11.020

1 reference

3 August 2017

1 reference