A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses (Q34539842)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27608667%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses (English)

1 reference

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22 March 2020

1 reference

16

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22 March 2020

Katie A Howell

4

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22 March 2020

Rohit K Jangra

10

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22 March 2020

Zachary A Bornholdt

13

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22 March 2020

Andrew I. Flyak

14

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22 March 2020

Erica Ollmann Saphire

15

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22 March 2020

John M Dye

18

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22 March 2020

20

Kartik Chandran

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22 March 2020

author name string

Anna Z Wec

1

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22 March 2020

Elisabeth K Nyakatura

2

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22 March 2020

Andrew S Herbert

3

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22 March 2020

Frederick W Holtsberg

5

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22 March 2020

Russell R Bakken

6

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22 March 2020

Eva Mittler

7

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22 March 2020

John R Christin

8

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22 March 2020

Sergey Shulenin

9

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22 March 2020

Sushma Bharrhan

11

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22 March 2020

Ana I Kuehne

12

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22 March 2020

M Javad Aman

17

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22 March 2020

Jonathan R Lai

19

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22 March 2020

language of work or name

English

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publication date

8 September 2016

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22 March 2020

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22 March 2020

volume

354

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22 March 2020

issue

6310

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22 March 2020

page(s)

350-354

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A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

22 March 2020

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1 reference

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Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

7 July 2018

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Chasing Ebola through the Endosomal Labyrinth

7 July 2018

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Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak

7 July 2018

1 reference

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Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

7 July 2018

1 reference

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Discovery of an antibody for pan-ebolavirus therapy

7 July 2018

1 reference

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Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

7 July 2018

1 reference

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Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

7 July 2018

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Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1

7 July 2018

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Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses.

7 July 2018

1 reference

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Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

7 July 2018

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Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

7 July 2018

1 reference

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Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein.

7 July 2018

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Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes

7 July 2018

1 reference

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Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

7 July 2018

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Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.

7 July 2018

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Interferon α/β Receptor-Deficient Mice as a Model for Ebola Virus Disease.

7 July 2018

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Structural basis for Marburg virus neutralization by a cross-reactive human antibody

7 July 2018

1 reference

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Mechanism of human antibody-mediated neutralization of Marburg virus

7 July 2018

1 reference

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Alternative molecular formats and therapeutic applications for bispecific antibodies

7 July 2018

1 reference

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Structures of protective antibodies reveal sites of vulnerability on Ebola virus

7 July 2018

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Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1.

7 July 2018

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7 July 2018

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7 July 2018

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Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

7 July 2018

1 reference

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7 July 2018

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

7 July 2018

1 reference

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Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

7 July 2018

1 reference

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever

7 July 2018

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Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin.

7 July 2018

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Exploration of new chromophore structures leads to the identification of improved blue fluorescent proteins

21 January 2018

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The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel

21 January 2018

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IgBLAST: an immunoglobulin variable domain sequence analysis tool

21 January 2018

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Antibody internalization studied using a novel IgG binding toxin fusion

21 January 2018

1 reference

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Controlled Fab-arm exchange for the generation of stable bispecific IgG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAG3267

Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences

21 January 2018

1 reference

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A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry

21 January 2018

1 reference

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An antiviral role for the RNA interference machinery in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAG3267

Evaluation of immune globulin and recombinant interferon-alpha2b for treatment of experimental Ebola virus infections

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.AAG3267

Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda

21 January 2018

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Ebola virus-like particles protect from lethal Ebola virus infection

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAG3267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27608667%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27608667%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

27608667

1 reference