RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment (Q34515173)

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English	RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment	scientific article

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8 March 2020

RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment (English)

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8 March 2020

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8 March 2020

Ismail H. Ismail

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8 March 2020

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8 March 2020

Michael J. Hendzel

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8 March 2020

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Ross A Edwards

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8 March 2020

Greg L Hura

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8 March 2020

Andrew T Xiao

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8 March 2020

J N Mark Glover

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22 February 2016

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8 March 2020

Journal of Biological Chemistry

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8 March 2020

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8 March 2020

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8 March 2020

9396-9410

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8 March 2020

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

1 reference

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7 July 2018

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains

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7 July 2018

Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting

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7 July 2018

New insights into ubiquitin E3 ligase mechanism

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ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling

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7 July 2018

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

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7 July 2018

Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine

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7 July 2018

RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

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7 July 2018

Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B.

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Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source

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7 July 2018

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling

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7 July 2018

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

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7 July 2018

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

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7 July 2018

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

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7 July 2018

Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation

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7 July 2018

The ubiquitin code

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Mechanism of ubiquitylation by dimeric RING ligase RNF4

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E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP.

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

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7 July 2018

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The DNA Damage Response: Making It Safe to Play with Knives

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7 July 2018

Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient

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7 July 2018

Structural and functional characterization of the monomeric U-box domain from E4B

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7 July 2018

Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)

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Structure and flexibility within proteins as identified through small angle X-ray scattering

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Ubiquitin-binding domains

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7 July 2018

Pathways of ubiquitin conjugation

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12 December 2020

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10.1074/JBC.M116.715698

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8 March 2020

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8 March 2020

PubMed publication ID

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