Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone (Q34508348)

25277122

2 August 2017

title

Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone (English)

1 reference

2 August 2017

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25277122%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Debashish Sahay

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25277122%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Philippe Clézardin

10

1 reference

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4 June 2020

Olivier Peyruchaud

12

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4 June 2020

author name string

Raphael Leblanc

1

1 reference

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4 June 2020

Sue-Chin Lee

2

1 reference

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4 June 2020

Marion David

3

1 reference

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4 June 2020

Derek D Norman

5

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4 June 2020

Renukadevi Patil

6

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4 June 2020

Duane Miller

7

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4 June 2020

Johnny Ribeiro

9

1 reference

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4 June 2020

Gabor J Tigyi

11

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4 June 2020

language of work or name

English

0 references

publication date

2 October 2014

1 reference

2 August 2017

1 reference

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4 June 2020

volume

124

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4 June 2020

issue

20

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4 June 2020

page(s)

3141-3150

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Autotaxin in the crosshairs: taking aim at cancer and other inflammatory conditions

4 June 2020

cites work

1 reference

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Autotaxin: structure-function and signaling

7 July 2018

1 reference

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Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Role of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

7 July 2018

1 reference

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SnapShot: Bioactive lysophospholipids

7 July 2018

1 reference

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Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis

7 July 2018

1 reference

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Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells

7 July 2018

1 reference

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Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity

7 July 2018

1 reference

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The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation

7 July 2018

1 reference

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Contribution of platelets to tumour metastasis.

7 July 2018

1 reference

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Structural basis of substrate discrimination and integrin binding by autotaxin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.

7 July 2018

1 reference

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Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

7 July 2018

1 reference

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The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases

7 July 2018

1 reference

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Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.

7 July 2018

1 reference

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Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis

7 July 2018

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Expression, regulation and function of autotaxin in thyroid carcinomas

7 July 2018

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Angiostatin inhibits bone metastasis formation in nude mice through a direct anti-osteoclastic activity

7 July 2018

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The emerging role of lysophosphatidic acid in cancer

7 July 2018

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Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

7 July 2018

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Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone

7 July 2018

1 reference

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Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

7 July 2018

1 reference

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Integrin activation controls metastasis in human breast cancer

7 July 2018

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Antimetastatic effects associated with platelet reduction

7 July 2018

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Platelet—tumor-cell interactions in mice. The role of platelets in the spread of malignant disease

7 July 2018

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Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo

7 July 2018

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Uptake of plasma fibrinogen into the alpha granules of human megakaryocytes and platelets

7 July 2018

1 reference

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Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes

7 July 2018

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Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

7 July 2018

1 reference

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Platelet-derived nucleotides promote tumor-cell transendothelial migration and metastasis via P2Y2 receptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Serum lysophosphatidic acid is produced through diverse phospholipase pathways

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231421

Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions

27 October 2018

1 reference

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Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25277122

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25277122

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2014-04-568683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25277122%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25277122%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

25277122

1 reference

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