Myocardial gene therapy (Q34503413)

2 August 2017

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title

Myocardial gene therapy. (English)

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2 August 2017

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Jeffrey M Isner

1

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2 August 2017

language of work or name

English

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publication date

1 January 2002

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2 August 2017

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2 August 2017

volume

415

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2 August 2017

issue

6868

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2 August 2017

page(s)

234-239

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Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

2 August 2017

cites work

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7 January 2021

Arterial gene therapy for therapeutic angiogenesis in patients with peripheral artery disease

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7 January 2021

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

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7 January 2021

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

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7 January 2021

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

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7 January 2021

Use of the rabbit ear artery to serially assess foreign protein secretion after site-specific arterial gene transfer in vivo. Evidence that anatomic identification of successful gene transfer may underestimate the potential magnitude of transgene ex

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7 January 2021

Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease

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7 January 2021

Direct gene transfer into mouse muscle in vivo

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7 January 2021

In vivo analysis of intramuscular gene transfer in human subjects studied by on-line ultrasound imaging

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7 January 2021

Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium

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7 January 2021

Intraoperative multiplane transesophageal echocardiography for guiding direct myocardial gene transfer of vascular endothelial growth factor in patients with refractory angina pectoris

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7 January 2021

An improved plasmid DNA expression vector for direct injection into skeletal muscle

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7 January 2021

Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters

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7 January 2021

Differentiation of endothelium.

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7 January 2021

Comparison of transmyocardial revascularization with medical therapy in patients with refractory angina

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7 January 2021

Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease

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7 January 2021

Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor

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7 January 2021

Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia

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7 January 2021

In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

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7 January 2021

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

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7 January 2021

Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure

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7 January 2021

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

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7 January 2021

Prospects for gene therapy for heart failure

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7 January 2021

Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation

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7 January 2021

Adenoviral-mediated serca gene transfer into cardiac myocytes: how much is too much?

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7 January 2021

Effects of mutant and antisense RNA of phospholamban on SR Ca(2+)-ATPase activity and cardiac myocyte contractility

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7 January 2021

Catecholamines, cardiac beta-adrenergic receptors, and heart failure

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7 January 2021

Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery

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7 January 2021

Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors In vivo by ultrasound-guided injection or transcoronary delivery

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7 January 2021

Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction

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7 January 2021

Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity

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7 January 2021

Toward antiapoptosis as a new treatment modality

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7 January 2021

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

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7 January 2021

The bcl-2 Gene Product Prevents Programmed Cell Death of Ventricular Myocytes

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7 January 2021

Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

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7 January 2021

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

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7 January 2021

Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

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7 January 2021

Tight control of exogenous SERCA expression is required to obtain acceleration of calcium transients with minimal cytotoxic effects in cardiac myocytes

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7 January 2021

Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors

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7 January 2021

Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart

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7 January 2021

The well-tempered vessel

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7 January 2021

Fibrillar collagen and remodeling of dilated canine left ventricle

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7 January 2021

Progression of heart failure: a role for interstitial fibrosis

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7 January 2021

Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy

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7 January 2021

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

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7 January 2021

Coronary collateral development in swine after coronary artery occlusion

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7 January 2021

Use of synchrotron radiation microangiography to assess development of small collateral arteries in a rat model of hindlimb ischemia.

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7 January 2021

Isolation of putative progenitor endothelial cells for angiogenesis

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7 January 2021

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization

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7 January 2021

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

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7 January 2021

VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease

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7 January 2021

Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation

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7 January 2021

Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization

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7 January 2021

Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia

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7 January 2021

Transplacental carcinogenesis by stilbestrol

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7 January 2021

Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation

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7 January 2021

Identifiers

DOI

10.1038/415234A

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Dimensions Publication ID

2 August 2017

1015714386

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