tRNA modification enzymes GidA and MnmE: potential role in virulence of bacterial pathogens. (Q34486792)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310651%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

review article

2 references

13 November 2020

tRNA modification enzymes GidA and MnmE: potential role in virulence of bacterial pathogens (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310651%20AND%20SRC:MED&resulttype=core&format=json

bacterial infectious disease

21 February 2020

main subject

1 reference

PubMed

Escherichia coli proteins

13 November 2020

GTP phosphohydrolases

1 reference

28 September 2019

1 reference

2 November 2019

1 reference

20 November 2019

1 reference

31 August 2020

1 reference

13 November 2020

bacterial physiological phenomenon

1 reference

PubMed publication ID

25310651

transfer RNA

1 reference

PubMed publication ID

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310651%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Amin A Fadl

series ordinal

2

1 reference

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21 February 2020

language of work or name

English

0 references

publication date

10 October 2014

8 references

23 March 2019

28 September 2019

2 November 2019

20 November 2019

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21 February 2020

31 August 2020

26 September 2020

13 November 2020

International Journal of Molecular Sciences

8 references

23 March 2019

28 September 2019

2 November 2019

20 November 2019

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21 February 2020

31 August 2020

26 September 2020

13 November 2020

15

1 reference

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21 February 2020

issue

10

1 reference

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21 February 2020

page(s)

18267-18280

1 reference

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Creative Commons Attribution

21 February 2020

copyright license

7 references

23 March 2019

28 September 2019

2 November 2019

20 November 2019

31 August 2020

26 September 2020

13 November 2020

0 references

on focus list of Wikimedia project

ScienceSource

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Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U.

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Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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tRNA modification by GidA/MnmE is necessary for Streptococcus pyogenes virulence: a new strategy to make live attenuated strains

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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tRNA's wobble decoding of the genome: 40 years of modification

6 July 2018

1 reference

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Human mitochondrial diseases associated with tRNA wobble modification deficiency

6 July 2018

1 reference

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Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli

6 July 2018

1 reference

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Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element

6 July 2018

1 reference

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Structural alterations of the cysteine desulfurase IscS of Salmonella enterica serovar Typhimurium reveal substrate specificity of IscS in tRNA thiolation

6 July 2018

1 reference

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Role of 2,4-Diacetylphloroglucinol in the Interactions of the Biocontrol Pseudomonad Strain F113 with the Potato Cyst Nematode Globodera rostochiensis

6 July 2018

1 reference

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Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria--evolutionary implications

6 July 2018

1 reference

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The structure of the TrmE GTP-binding protein and its implications for tRNA modification

6 July 2018

1 reference

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The Era-like GTPase TrmE conditionally activates gadE and glutamate-dependent acid resistance in Escherichia coli.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA

6 July 2018

1 reference

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Molecular characterization of a glucose-inhibited division gene, gidA, that regulates cytotoxic enterotoxin of Aeromonas hydrophila

6 July 2018

1 reference

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The cysteine desulfurase IscS is required for synthesis of all five thiolated nucleosides present in tRNA from Salmonella enterica serovar typhimurium

6 July 2018

1 reference

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Requirement for IscS in biosynthesis of all thionucleosides in Escherichia coli

6 July 2018

1 reference

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A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation

6 July 2018

1 reference

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Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12 S rRNA A1555G mutation

6 July 2018

1 reference

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Global regulation by gidA in Pseudomonas syringae

6 July 2018

1 reference

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GidA is an FAD-binding protein involved in development of Myxococcus xanthus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift

6 July 2018

1 reference

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Improvement of reading frame maintenance is a common function for several tRNA modifications

6 July 2018

1 reference

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Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima

6 July 2018

1 reference

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The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae.

6 July 2018

1 reference

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The RNA modification database--1998

6 July 2018

1 reference

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Characterization of Helicobacter pylori dapE and construction of a conditionally lethal dapE mutant

6 July 2018

1 reference

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The modified nucleoside 2-methylthio-N6-isopentenyladenosine in tRNA of Shigella flexneri is required for expression of virulence genes

6 July 2018

1 reference

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Multiple loci of Pseudomonas syringae pv. syringae are involved in pathogenicity on bean: restoration of one lesion-deficient mutant requires two tRNA genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

Gene transcription and chromosome replication in Escherichia coli

6 July 2018

1 reference

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MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

vacC, a virulence-associated chromosomal locus of Shigella flexneri, is homologous to tgt, a gene encoding tRNA-guanine transglycosylase (Tgt) of Escherichia coli K-12

6 July 2018

1 reference

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Genetic evidence that the gacA gene encodes the cognate response regulator for the lemA sensor in Pseudomonas syringae

6 July 2018

1 reference

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Novel E. coli mutants deficient in biosynthesis of 5-methylaminomethyl-2-thiouridine

6 July 2018

1 reference

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Transfer RNA(5-methylaminomethyl-2-thiouridine)-methyltransferase from Escherichia coli K-12 has two enzymatic activities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

AsnC, a multifunctional regulator of genes located around the replication origin of Escherichia coli, oriC.

6 July 2018

1 reference

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Transcription in the region of the replication origin, oriC, of Escherichia coli: termination of asnC transcripts.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

Concurrent transcription from the gid and mioC promoters activates replication of an Escherichia coli minichromosome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

The lemA gene required for pathogenicity of Pseudomonas syringae pv. syringae on bean is a member of a family of two-component regulators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227215

MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli

6 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Snapshots of tRNA sulphuration via an adenylated intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Virulence characteristics of Salmonella following deletion of genes encoding the tRNA modification enzymes GidA and MnmE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Biological and virulence characteristics of Salmonella enterica serovar Typhimurium following deletion of glucose-inhibited division (gidA) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

GidA expression in Salmonella is modulated under certain environmental conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Identification of Streptococcus suis serotype 2 genes preferentially expressed in the natural host

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Microbial products trigger amino acid exudation from plant roots

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

2,4-diacetylphloroglucinol alters plant root development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

The tRNA-modifying function of MnmE is controlled by post-hydrolysis steps of its GTPase cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS151018267

Promoters of the atp operon coding for the membrane-bound ATP synthase of Escherichia coli Mapped by Tn 10 insertion mutations

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25310651

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS151018267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310651%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310651%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

25310651

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310651%20AND%20SRC:MED&resulttype=core&format=json