Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function (Q34483937)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25314967%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function (English)

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21 February 2020

13

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15

Jonathan D Wren

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21 February 2020

author name string

Xiaolei Liu

1

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21 February 2020

Satish Pasula

2

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21 February 2020

Hoogeun Song

3

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21 February 2020

Kandice L Tessneer

4

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21 February 2020

Yunzhou Dong

5

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21 February 2020

Scott Hahn

6

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21 February 2020

Tadayuki Yago

7

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Megan L Brophy

8

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21 February 2020

Baojun Chang

9

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21 February 2020

Xiaofeng Cai

10

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21 February 2020

Hao Wu

11

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21 February 2020

John McManus

12

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21 February 2020

Constantin Georgescu

14

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21 February 2020

Courtney Griffin

16

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21 February 2020

Lijun Xia

17

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21 February 2020

R Sathish Srinivasan

18

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21 February 2020

Hong Chen

19

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21 February 2020

publication date

14 October 2014

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21 February 2020

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21 February 2020

volume

7

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21 February 2020

issue

347

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page(s)

ra97

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Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency

21 February 2020

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Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

6 July 2018

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Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling

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An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation.

6 July 2018

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Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation

6 July 2018

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Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling

6 July 2018

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RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

6 July 2018

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Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

6 July 2018

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6 July 2018

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Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

6 July 2018

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Selective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculi

6 July 2018

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Prox1 expression is negatively regulated by miR-181 in endothelial cells

6 July 2018

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Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

6 July 2018

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Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development

6 July 2018

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Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

6 July 2018

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Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis

6 July 2018

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Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.

6 July 2018

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Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3.

6 July 2018

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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

6 July 2018

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Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis

6 July 2018

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Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice

6 July 2018

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FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

6 July 2018

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The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module

6 July 2018

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Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

6 July 2018

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Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

6 July 2018

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A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities

6 July 2018

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A mouse lymphoid endothelial cell line immortalized by simian virus 40 binds lymphocytes and retains functional characteristics of normal endothelial cells

6 July 2018

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Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

6 July 2018

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Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

21 January 2018

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Interstitial flow differentially stimulates blood and lymphatic endothelial cell morphogenesis in vitro

21 January 2018

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H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice

21 January 2018

1 reference

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Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

21 January 2018

1 reference

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Shear stress stimulation of p130(cas) tyrosine phosphorylation requires calcium-dependent c-Src activation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25314967

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prox1 function is required for the development of the murine lymphatic system

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25314967

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.2005413

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25314967%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25314967%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

25314967

1 reference