Precision cancer mouse models through genome editing with CRISPR-Cas9. (Q34480103)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060510%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

review article

1 reference

title

Precision cancer mouse models through genome editing with CRISPR-Cas9 (English)

1 reference

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16 February 2020

0 references

0 references

1 reference

1

1 reference

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16 February 2020

Zachary Kennedy

2

1 reference

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16 February 2020

author name string

Daniel G Anderson

3

1 reference

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16 February 2020

Hao Yin

4

1 reference

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16 February 2020

Wen Xue

5

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16 February 2020

publication date

9 June 2015

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16 February 2020

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16 February 2020

volume

7

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16 February 2020

issue

1

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16 February 2020

page(s)

53

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Applications of the CRISPR-Cas9 system in cancer biology

16 February 2020

cites work

1 reference

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A versatile reporter system for CRISPR-mediated chromosomal rearrangements.

6 July 2018

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Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

6 July 2018

1 reference

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Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.

6 July 2018

1 reference

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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

6 July 2018

1 reference

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In vivo genome editing using Staphylococcus aureus Cas9

6 July 2018

1 reference

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Biotechnology. A prudent path forward for genomic engineering and germline gene modification

6 July 2018

1 reference

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Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

6 July 2018

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An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo

6 July 2018

1 reference

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Rational design of a split-Cas9 enzyme complex

6 July 2018

1 reference

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Inducible in vivo genome editing with CRISPR-Cas9

6 July 2018

1 reference

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A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

6 July 2018

1 reference

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Small molecules enhance CRISPR genome editing in pluripotent stem cells.

6 July 2018

1 reference

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Therapeutic genome editing: prospects and challenges

6 July 2018

1 reference

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A split-Cas9 architecture for inducible genome editing and transcription modulation

6 July 2018

1 reference

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CRISPR-Cas9-based photoactivatable transcription system.

6 July 2018

1 reference

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Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds

6 July 2018

1 reference

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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

6 July 2018

1 reference

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Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

6 July 2018

1 reference

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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

6 July 2018

1 reference

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Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology

6 July 2018

1 reference

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Genome editing. The new frontier of genome engineering with CRISPR-Cas9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

6 July 2018

1 reference

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

6 July 2018

1 reference

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CRISPR-Cas9 knockin mice for genome editing and cancer modeling

6 July 2018

1 reference

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CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems

6 July 2018

1 reference

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Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9.

6 July 2018

1 reference

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Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.

6 July 2018

1 reference

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

6 July 2018

1 reference

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Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

6 July 2018

1 reference

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

6 July 2018

1 reference

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Improved vectors and genome-wide libraries for CRISPR screening

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

TALEN-mediated somatic mutagenesis in murine models of cancer

6 July 2018

1 reference

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Generating genetically modified mice using CRISPR/Cas-mediated genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

6 July 2018

1 reference

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Development and applications of CRISPR-Cas9 for genome engineering

6 July 2018

1 reference

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Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system

6 July 2018

1 reference

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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia

6 July 2018

1 reference

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

6 July 2018

1 reference

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Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

6 July 2018

1 reference

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Targeted genomic rearrangements using CRISPR/Cas technology

6 July 2018

1 reference

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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

6 July 2018

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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

6 July 2018

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A guide to genome engineering with programmable nucleases

6 July 2018

1 reference

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Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

6 July 2018

1 reference

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CRISPR-Cas systems for editing, regulating and targeting genomes

6 July 2018

1 reference

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Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

6 July 2018

1 reference

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

6 July 2018

1 reference

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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

6 July 2018

1 reference

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Discovery and saturation analysis of cancer genes across 21 tumour types

6 July 2018

1 reference

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Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells

6 July 2018

1 reference

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Genome-scale CRISPR-Cas9 knockout screening in human cells

6 July 2018

1 reference

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Genetic screens in human cells using the CRISPR-Cas9 system

6 July 2018

1 reference

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Correction of a genetic disease in mouse via use of CRISPR-Cas9.

6 July 2018

1 reference

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Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

6 July 2018

1 reference

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Repurposing CRISPR/Cas9 for in situ functional assays.

6 July 2018

1 reference

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CRISPR interference (CRISPRi) for sequence-specific control of gene expression

6 July 2018

1 reference

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Cas9 as a versatile tool for engineering biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

6 July 2018

1 reference

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One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

6 July 2018

1 reference

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 July 2018

1 reference

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

6 July 2018

1 reference

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

DNA targeting specificity of RNA-guided Cas9 nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

RNA-programmed genome editing in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

RNA-guided human genome engineering via Cas9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Multiplex genome engineering using CRISPR/Cas systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Life in the fast lane: mammalian disease models in the genomics era.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Hallmarks of Cancer: The Next Generation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Cancer modeling in the modern era: progress and challenges

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

6 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4460969

Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice.

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-015-0178-7

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-015-0178-7

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-015-0178-7

E-CRISP: fast CRISPR target site identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-015-0178-7

Microhomology-based choice of Cas9 nuclease target sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-015-0178-7

10.1186/S13073-015-0178-7

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060510%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060510%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

26060510

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060510%20AND%20SRC:MED&resulttype=core&format=json