Nonlipid-lowering effects of statins (Q34466935)

2 August 2017

title

Nonlipid-lowering effects of statins (English)

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2 August 2017

2

Ulf Landmesser

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2 August 2017

Sajoscha Sorrentino

1

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2 August 2017

publication date

1 December 2005

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Current treatment options in cardiovascular medicine

2 August 2017

published in

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2 August 2017

volume

7

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2 August 2017

issue

6

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2 August 2017

page(s)

459-466

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Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

2 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS11936-005-0031-1

Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11936-005-0031-1

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11936-005-0031-1

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11936-005-0031-1

Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture

21 January 2018

1 reference

12 December 2020

Nitric oxide insufficiency, platelet activation, and arterial thrombosis

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12 December 2020

HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells

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12 December 2020

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

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12 December 2020

Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair

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12 December 2020

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

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12 December 2020

Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy

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12 December 2020

Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy

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12 December 2020

Endothelial function: a critical determinant in atherosclerosis?

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12 December 2020

Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study

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12 December 2020

Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation

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12 December 2020

Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase

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12 December 2020

Role of oxidative stress in atherosclerosis

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12 December 2020

Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial

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12 December 2020

Increased myocardial NADPH oxidase activity in human heart failure

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12 December 2020

Is there a vulnerable plaque?

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12 December 2020

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

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12 December 2020

Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

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12 December 2020

Statin therapy is associated with improved survival in ischemic and non-ischemic heart failure

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12 December 2020

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines

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12 December 2020

Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions

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12 December 2020

The relationship between cholesterol and survival in patients with chronic heart failure

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12 December 2020

Rapid Effect of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition on Coronary Endothelial Function

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12 December 2020

Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins

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12 December 2020

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

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12 December 2020

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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12 December 2020

Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment

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12 December 2020

Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and Rac1 GTPase.

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12 December 2020

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12 December 2020

Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes: further evidence for the existence of the "vulnerable" patient

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12 December 2020

Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor

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12 December 2020

Inflammation and atherosclerosis

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12 December 2020

Statins as a newly recognized type of immunomodulator

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12 December 2020

Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture

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12 December 2020

Inflammation, atherosclerosis, and coronary artery disease

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12 December 2020

Atherosclerosis — An Inflammatory Disease

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12 December 2020

C-reactive protein levels and outcomes after statin therapy

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12 December 2020

HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth muscle and endothelial cells

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12 December 2020

Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin

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12 December 2020

Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition

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12 December 2020

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

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12 December 2020

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

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12 December 2020

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

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12 December 2020

HMG-CoA reductase inhibition improves endothelial cell function and inhibits smooth muscle cell proliferation in human saphenous veins

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12 December 2020

Simvastatin versus ezetimibe: pleiotropic and lipid-lowering effects on endothelial function in humans

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12 December 2020

HMG-CoA reductase inhibitors improve acute ischemic stroke outcome

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12 December 2020

Effect of pravastatin on outcomes after cardiac transplantation.

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12 December 2020

Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells

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12 December 2020

10.1007/S11936-005-0031-1

Identifiers

DOI

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2 August 2017

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