Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes (Q34464759)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

1 reference

1 reference

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Francisco J Rupérez

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Coral Barbas

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

José Tuñón

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Oscar Lorenzo

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Elisa Ramírez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Mercedes Klett-Mingo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sara Ares-Carrasco

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Belén Picatoste

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Alicia Caro-Vadillo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jesús Egido

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

21 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

Cardiovascular Diabetology

1 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

Sitagliptin reduces cardiac apoptosis, hypertrophy and fibrosis primarily by insulin-dependent mechanisms in experimental type-II diabetes. Potential roles of GLP-1 isoforms

1 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Aldosterone receptor antagonists in cardiovascular disease: a review of the recent literature and insight into potential future indications.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Safety of mineralocorticoid receptor antagonists in patients receiving hemodialysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Mineralocorticoid receptor activation in myocardial infarction and failure: recent advances

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Chronic hyperglycemia and subclinical myocardial injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Extrarenal effects of aldosterone.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Mitochondrial dysfunction in diabetic cardiomyopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

A murine model of isolated cardiac steatosis leads to cardiomyopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

The regulation of cell growth and survival by aldosterone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Differential actions of eplerenone and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitro.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Myocardial fatty acid metabolism in health and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Aldosterone directly induces myocyte apoptosis through calcineurin-dependent pathways.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Mineralocorticoid receptor blockade: new insights into the mechanism of action in patients with cardiovascular disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Eplerenone: a selective aldosterone blocker.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Renin-angiotensin system and renal damage: emerging data on angiotensin II as a proinflammatory mediator.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Lipotoxic heart disease in obese rats: implications for human obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Stable transfection of fatty acid translocase (CD36) in a rat heart muscle cell line (H9c2).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Congestive heart failure in the diabetic

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Intensive glycemic control has no impact on the risk of heart failure in type 2 diabetic patients: evidence from a 37,229 patient meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Transcriptional inhibition of the human insulin receptor gene by aldosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Impact of excess aldosterone on glucose homeostasis in adult male rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Prostate effect in dogs with the aldosterone receptor blocker eplerenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Renin-angiotensin blockade attenuates cardiac myofibrillar remodelling in chronic diabetes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222723

Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats

27 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-12-172

Proteome changes in the myocardium of experimental chronic diabetes and hypertension

21 January 2018

1 reference

12 December 2020

Myocardial cell death in human diabetes

1 reference

12 December 2020

Purification, immunochemical quantification and localization in rat heart of putative fatty acid translocase (FAT/CD36)

1 reference

12 December 2020

PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet

1 reference

12 December 2020

Aldosterone receptor antagonism exacerbates intrarenal angiotensin II augmentation in ANG II-dependent hypertension

1 reference

12 December 2020

Identifiers

DOI

10.1186/1475-2840-12-172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24261558

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261558%20AND%20SRC:MED&resulttype=core&format=json