Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk (Q34457337)

2 August 2017

title

Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk (English)

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2 August 2017

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3

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Aldons J Lusis

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Stephen G Ellis

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Danielle M Brennan

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Marie-Luise Brennan

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2 August 2017

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Stanley L Hazen

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2 August 2017

Tamali Bhattacharyya

1

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2 August 2017

Stephen J Nicholls

2

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2 August 2017

Renliang Zhang

4

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2 August 2017

Xia Yang

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2 August 2017

David Schmitt

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2 August 2017

Xiaoming Fu

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2 August 2017

Mingyuan Shao

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2 August 2017

Hooman Allayee

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2 August 2017

language of work or name

English

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publication date

1 March 2008

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The Journal of the American Medical Association

2 August 2017

published in

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2 August 2017

volume

299

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2 August 2017

issue

11

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2 August 2017

page(s)

1265-1276

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Genomewide association analysis of coronary artery disease

2 August 2017

cites work

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Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease

6 July 2018

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Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?

6 July 2018

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Genetic basis of atherosclerosis: part I: new genes and pathways

6 July 2018

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The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis

6 July 2018

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Paraoxonase gene polymorphisms, oxidative stress, and diseases

6 July 2018

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Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials

6 July 2018

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Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids

6 July 2018

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Paraoxonase and atherosclerosis

6 July 2018

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Polymorphisms in the human paraoxonase (PON1) promoter

6 July 2018

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Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

6 July 2018

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Paraoxonase genes and disease

6 July 2018

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Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

6 July 2018

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Use of commercial record linkage software and vital statistics to identify patient deaths

6 July 2018

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Evaluating the yield of medical tests

6 July 2018

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The human serum paraoxonase/arylesterase polymorphism.

6 July 2018

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Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation

6 July 2018

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Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies

27 October 2018

1 reference

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Evaluating a new marker's predictive contribution

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014051

Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions

27 October 2018

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Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II.

27 October 2018

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Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice

27 October 2018

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Human paraoxonase 1 gene polymorphisms and the risk of coronary heart disease: a community-based study

27 October 2018

1 reference

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Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation

27 October 2018

1 reference

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Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014051

Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014051

Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein

27 October 2018

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12 December 2020

The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux

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12 December 2020

Validating a prognostic model

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12 December 2020

Problems with Genome-Wide Association Studies

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12 December 2020

Scanning the genome for coronary risk

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12 December 2020

Identifiers

DOI

10.1001/JAMA.299.11.1265

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2 August 2017

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2 August 2017

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