Activation of NFAT signaling in podocytes causes glomerulosclerosis (Q34455455)

2 August 2017

title

Activation of NFAT signaling in podocytes causes glomerulosclerosis (English)

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2 August 2017

1 reference

2

George Jarad

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2 August 2017

8

Jeffrey H Miner

1 reference

2 August 2017

Yinqiu Wang

1

1 reference

2 August 2017

Piyush Tripathi

3

1 reference

2 August 2017

Minggui Pan

4

1 reference

2 August 2017

Jeanette Cunningham

5

1 reference

2 August 2017

Daniel R Martin

6

1 reference

2 August 2017

Helen Liapis

7

1 reference

2 August 2017

Feng Chen

9

1 reference

2 August 2017

publication date

22 July 2010

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Journal of the American Society of Nephrology

2 August 2017

published in

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2 August 2017

volume

21

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2 August 2017

issue

10

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2 August 2017

page(s)

1657-1666

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Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells

2 August 2017

cites work

1 reference

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TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.

6 July 2018

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Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease

6 July 2018

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6 July 2018

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6 July 2018

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The spectrum of focal segmental glomerulosclerosis: new insights

6 July 2018

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Focal segmental glomerulosclerosis: recent advances

6 July 2018

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Development of the renal glomerulus: good neighbors and good fences

6 July 2018

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Podocyte injury in focal segmental glomerulosclerosis: Lessons from animal models (a play in five acts).

6 July 2018

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6 July 2018

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NFAT signaling and the invention of vertebrates

6 July 2018

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6 July 2018

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Genetics of focal segmental glomerulosclerosis

6 July 2018

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Calcineurin-NFATc signaling pathway regulates AQP2 expression in response to calcium signals and osmotic stress

6 July 2018

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TRPC6 in glomerular health and disease: what we know and what we believe

6 July 2018

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Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

6 July 2018

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Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier

6 July 2018

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The podocyte's response to injury: role in proteinuria and glomerulosclerosis

6 July 2018

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The renin-angiotensin system in glomerular podocytes: mediator of glomerulosclerosis and link to hypertensive nephropathy

6 July 2018

1 reference

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Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation

6 July 2018

1 reference

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Podocyte injury and targeting therapy: an update

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

6 July 2018

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Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.

6 July 2018

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Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery.

6 July 2018

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DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice

6 July 2018

1 reference

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Urinary excretion of viable podocytes in health and renal disease

6 July 2018

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Cell biology of the glomerular podocyte

6 July 2018

1 reference

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Angiotensin II inhibits human trophoblast invasion through AT1 receptor activation

6 July 2018

1 reference

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NFAT signaling: choreographing the social lives of cells

6 July 2018

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NFAT signaling in vertebrate development

6 July 2018

1 reference

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Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

6 July 2018

1 reference

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Calcium, calcineurin, and the control of transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Angiotensin II upregulates RAGE expression on podocytes: role of AT2 receptors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Cardiac cell hypertrophy in vitro: role of calcineurin/NFAT as Ca2+ signal integrators

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Activation of a local renin angiotensin system in podocytes by glucose

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Activation of the renin-angiotensin system within podocytes in diabetes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Calcineurin/NFAT signaling in osteoblasts regulates bone mass

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Podocytes that detach in experimental membranous nephropathy are viable.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Insulin-like growth factor-I induces renal cell hypertrophy via a calcineurin-dependent mechanism

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Endothelin-1 induces cyclooxygenase-2 expression via nuclear factor of activated T-cell transcription factor in glomerular mesangial cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Podocyte-specific expression of cre recombinase in transgenic mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013542

Signaling to gene expression: calcium, calcineurin and NFAT

27 October 2018

1 reference

12 December 2020

Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes

1 reference

12 December 2020

Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes

1 reference

12 December 2020

Podocytes as a target for treatment with ACE inhibitors and/or angiotensin-receptor blockers

1 reference

12 December 2020

Viable podocytes detach in experimental diabetic nephropathy: potential mechanism underlying glomerulosclerosis

1 reference

12 December 2020

Treatment of focal segmental glomerulosclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2009121253

1 reference

2 August 2017

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2 August 2017

1 reference