Structural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1 (Q34452689)

2 August 2017

title

Structural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1 (English)

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https://api.crossref.org/works/10.1074/JBC.M110.159202

9 August 2024

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9 August 2024

2

Jens O. Lagerstedt

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9 August 2024

8

Robert R. Rigor

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9 August 2024

9

John C. Voss

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9 August 2024

11

Stine F. Pedersen

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9 August 2024

author name string

Gabriel Bjerre

3

1 reference

2 August 2017

Biao Shi

4

1 reference

2 August 2017

Madhu Budamagunta

5

1 reference

2 August 2017

Stine Meinild

7

1 reference

2 August 2017

Eva B. Nygaard

1

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9 August 2024

Kristian A. Poulsen

6

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9 August 2024

Peter M. Cala

10

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9 August 2024

language of work or name

English

0 references

publication date

25 October 2010

1 reference

2 August 2017

number of pages

15

1 reference

full work available at URL

inferred from page(s)

http://www.jbc.org/article/S0021925820542543/pdf

file format

Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20974853

http://intl.jbc.org/cgi/content/abstract/286/1/634

9 August 2024

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20974853/pdf/?tool=EBI

9 August 2024

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Portable Document Format

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20974853/?tool=EBI

9 August 2024

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https://europepmc.org/articles/PMC3013023

9 August 2024

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https://europepmc.org/articles/PMC3013023?pdf=render

9 August 2024

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content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20974853

https://doi.org/10.1074/jbc.m110.159202

9 August 2024

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https://api.elsevier.com/content/article/PII:S0021925820542543?httpAccept=text/xml

9 August 2024

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https://api.elsevier.com/content/article/PII:S0021925820542543?httpAccept=text/plain

9 August 2024

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https://syndication.highwire.org/content/doi/10.1074/jbc.M110.159202

9 August 2024

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Journal of Biological Chemistry

9 August 2024

published in

1 reference

2 August 2017

volume

286

1 reference

2 August 2017

issue

1

1 reference

2 August 2017

page(s)

634-648

1 reference

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

High-resolution structure of a Na+/H+ antiporter dimer obtained by pulsed electron paramagnetic resonance distance measurements

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Mechanism of Na+/H+ antiporting.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Functional and structural interactions of the transmembrane domain X of NhaA, Na+/H+ antiporter of Escherichia coli, at physiological pH.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Physiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Glutamate 346 of human Na+-H+ exchanger NHE1 is crucial for modulating both the affinity for Na+ and the interaction with amiloride derivatives

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Diversity of the mammalian sodium/proton exchanger SLC9 gene family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

SWISS-MODEL: An automated protein homology-modeling server

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

3D-Jury: a simple approach to improve protein structure predictions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Estimation of inter-residue distances in spin labeled proteins at physiological temperatures: experimental strategies and practical limitations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Second-site revertants of a low-sodium-affinity mutant of the Na+/H+ exchanger reveal the participation of TM4 into a highly constrained sodium-binding site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Identifying conformational changes with site-directed spin labeling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

A novel topology model of the human Na(+)/H(+) exchanger isoform 1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Cloning and expression of the Na+/H+ exchanger from Amphiuma RBCs: resemblance to mammalian NHE1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Major facilitator superfamily

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

A point mutation of the Na+/H+ exchanger gene (NHE1) and amplification of the mutated allele confer amiloride resistance upon chronic acidosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Mutational analysis of transmembrane histidines in the amiloride-sensitive Na+/H+ exchanger

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Hyperpolarization-activated chloride currents in Xenopus oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Impaired cell volume regulation in Na(+)-H+ exchange-deficient mutants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

A delayed rectifier potassium current in Xenopus oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013023

Identification of sites in the second exomembrane loop and ninth transmembrane helix of the mammalian Na+/H+ exchanger important for drug recognition and cation translocation.

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Dimeric structure of human Na+/H+ exchanger isoform 1 overproduced in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Structural modeling of dual-affinity purified Pho84 phosphate transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Site-directed spin labeling demonstrates that transmembrane domain XII in the lactose permease of Escherichia coli is an alpha-helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Elucidating conformational changes in the gamma-aminobutyric acid transporter-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

A radioactive uptake assay to measure ion transport across ion channel-containing liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Unraveling functional and structural interactions between transmembrane domains IV and XI of NhaA Na+/H+ antiporter of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

EPR-detected folding kinetics of externally located cysteine-directed spin-labeled mutants of iso-1-cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.159202

Mapping electron paramagnetic resonance spin label conformations by the simulated scaling method

21 January 2018

1 reference

12 December 2020

Delineation of transmembrane domains of the Na+/H+ exchanger that confer sensitivity to pharmacological antagonists

1 reference

12 December 2020

Biosynthesis and cell surface delivery of the NHE1 isoform of Na+/H+ exchanger in A6 cells

1 reference

12 December 2020

Conformation of T4 lysozyme in solution. Hinge-bending motion and the substrate-induced conformational transition studied by site-directed spin labeling

1 reference

12 December 2020

Random mutagenesis reveals a novel site involved in inhibitor interaction within the fourth transmembrane segment of the Na+/H+ exchanger-1

1 reference

12 December 2020

An NMR investigation of the conformational effect of nitroxide spin labels on Ala-rich helical peptides

1 reference

12 December 2020

Journal of Magnetic Resonance

30

47

515

Froncisz

1982

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.159202

9 August 2024

Identifiers

1 reference

2 August 2017

1 reference

2 August 2017

1 reference