Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes (Q34452028)

2 August 2017

title

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes (English)

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2 August 2017

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14

J. Hardy

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19

K. Duff

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1 December 2024

author name string

L. Holcomb

1

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1 December 2024

M. N. Gordon

2

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1 December 2024

E. McGowan

3

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1 December 2024

X. Yu

4

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S. Benkovic

5

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P. Jantzen

6

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K. Wright

7

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I. Saad

8

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1 December 2024

R. Mueller

9

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1 December 2024

D. Morgan

10

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S. Sanders

11

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C. Zehr

12

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K. O'Campo

13

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C. M. Prada

15

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C. Eckman

16

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S. Younkin

17

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K. Hsiao

18

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language of work or name

English

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publication date

1 January 1998

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2 August 2017

January 1998

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9427614

full work available at URL

1 December 2024

http://www.nature.com/articles/nm0198-097

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https://api.crossref.org/works/10.1038/NM0198-097

http://www.nature.com/articles/nm0198-097.pdf

1 December 2024

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/NM0198-097

1 December 2024

1 reference

2 August 2017

volume

4

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2 August 2017

issue

1

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2 August 2017

page(s)

97-100

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Amyloid, the presenilins and Alzheimer's disease

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Dissociable effects of selective lesions to hippocampal subsystems on exploratory behavior, contextual learning, and spatial learning

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Hippocampal morphology and open-field behavior in Mus musculus domesticus and Mus spretus inbred mice

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Absence of an association between motor coordination and spatial orientation in lurcher mutant mice.

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat

1 reference

https://api.crossref.org/works/10.1038%2FNM0198-097

7 January 2021

Identifiers

DOI

10.1038/NM0198-097

1 reference

2 August 2017

1 reference