Translocations of the RARalpha gene in acute promyelocytic leukemia (Q34435522)

2 August 2017

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title

Translocations of the RARalpha gene in acute promyelocytic leukemia (English)

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2 August 2017

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4

S Waxman

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2 August 2017

5

J D Licht

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2 August 2017

A Zelent

1

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2 August 2017

F Guidez

series ordinal

2

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2 August 2017

A Melnick

series ordinal

3

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2 August 2017

language of work or name

English

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publication date

1 October 2001

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2 August 2017

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2 August 2017

volume

20

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2 August 2017

issue

49

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2 August 2017

page(s)

7186-7203

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Crystal structure of the BTB domain from PLZF

2 August 2017

cites work

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Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia

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Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

21 January 2018

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The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase

21 January 2018

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The POZ domain: a conserved protein-protein interaction motif

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Plzf regulates limb and axial skeletal patterning

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RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

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Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

21 January 2018

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Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17

21 January 2018

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Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha)

21 January 2018

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Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis

21 January 2018

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Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: identification of the YY1 binding site at the 5' enhancer region

21 January 2018

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Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth

21 January 2018

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BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

21 January 2018

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Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia

21 January 2018

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PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors

21 January 2018

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Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha

21 January 2018

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NuMA is required for the proper completion of mitosis.

21 January 2018

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NuMA, a nuclear protein involved in mitosis and nuclear reformation.

21 January 2018

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Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis

21 January 2018

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Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain

21 January 2018

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STATs and Gene Regulation

21 January 2018

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Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein

21 January 2018

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Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF

21 January 2018

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Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Identification of a nuclear domain with deacetylase activity.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Regulation of p53 activity in nuclear bodies by a specific PML isoform

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

21 January 2018

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Chromosome movement in mitosis requires microtubule anchorage at spindle poles

21 January 2018

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

21 January 2018

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The function of PML in p53-dependent apoptosis

21 January 2018

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Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

21 January 2018

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GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA

21 January 2018

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Two critical hits for promyelocytic leukemia

21 January 2018

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Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The morphological relationship in electron microscopy between NOR-silver proteins and intranucleolar chromatin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor α (RARα) and PLZF-RARα oncoproteins associated with acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Down-regulation of nucleophosmin/B23 during retinoic acid-induced differentiation of human promyelocytic leukemia HL-60 cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

21 January 2018

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Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

21 January 2018

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Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Sequence-specific DNA Binding and Transcriptional Regulation by the Promyelocytic Leukemia Zinc Finger Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

C23 interacts with B23, a putative nucleolar-localization-signal-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Role of the histone deacetylase complex in acute promyelocytic leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Repression of TFIIH Transcriptional Activity and TFIIH-Associated cdk7 Kinase Activity at Mitosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Oncogenic Transcription Factors in the Human Acute Leukemias

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Human-specific nuclear protein that associates with the polar region of the mitotic apparatus: distribution in a human/hamster hybrid cell

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The RXR heterodimers and orphan receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

ROG, repressor of GATA, regulates the expression of cytokine genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

A bcr-3 isoform of RARalpha-PML potentiates the development of PML-RARalpha-driven acute promyelocytic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

A novel zinc finger coiled-coil domain in a family of nuclear proteins

21 January 2018

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

21 January 2018

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Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.

21 January 2018

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The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The RAR alpha-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Assignment of the nuclear mitotic apparatus protein NuMA gene to human chromosome 11q13

21 January 2018

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Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin

21 January 2018

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Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

21 January 2018

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Stimulation of calf thymus DNA polymerase alpha activity by nucleolar protein B23

21 January 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

NuMA: an unusually long coiled-coil related protein in the mammalian nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The nuclear-mitotic apparatus protein is important in the establishment and maintenance of the bipolar mitotic spindle apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Analysis of the joining sequences of the t(15;17) translocation in human acute promyelocytic leukemia: sequence non-specific recombination between the PML and RARA genes within identical short stretches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Altered Hox expression and segmental identity in Mll-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Effects of actinomycin D analogs on nucleolar phosphoprotein B23 (37,000 daltons/pI 5.1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Association of nuclear matrix proteins with granular and threaded nuclear bodies in cell lines undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Molecular analysis of simple variant translocations in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Nucleophosmin/B23 (NPM) oligomer is a major and stable entity in HeLa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Increased stability of nucleophosmin/B23 in anti-apoptotic effect of ras during serum deprivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Erythropoietin-induced erythroid differentiation of the human erythroleukemia cell line TF-1 correlates with impaired STAT5 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Acute promyelocytic leukaemia with t(11;17)(q23;q12‐21) and a good initial response to prolonged ATRA and combination chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

NuMA is a component of an insoluble matrix at mitotic spindle poles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Interaction of nucleolar phosphoprotein B23 with nucleic acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Biology and treatment of acute promyelocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Cleavage of the nuclear matrix protein NuMA during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Heterotypic smooth muscle cell/endothelial cell interactions differ between species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Nuclear matrix proteins as structural and functional components of the mitotic apparatus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Over-expression of nucleophosmin/B23 decreases the susceptibility of human leukemia HL-60 cells to retinoic acid-induced differentiation and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Down-regulation of nucleophosmin/B23 mRNA delays the entry of cells into mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Isolation of human NuMA protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Nucleophosmin/B23 regulates the susceptibility of human leukemia HL-60 cells to sodium butyrate-induced apoptosis and inhibition of telomerase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Novel retinoic acid receptor-alpha transcripts in acute promyelocytic leukemia responsive to all-trans-retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Differentiation of t(5;17) variant acute promyelocytic leukemic blasts by all-trans retinoic acid

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Everything you have ever wanted to know about Yin Yang 1......

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Amount of the two major Ag-NOR proteins, nucleolin, and protein B23 is cell-cycle dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Immunofluorescence studies on proteins B23 and C23 in nucleoli of human lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

The impact of differential binding of wild-type RARalpha, PML-, PLZF- and NPM-RARalpha fusion proteins towards transcriptional co-activator, RIP-140, on retinoic acid responses in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Role of Protein Phosphorylation in Post-translational Regulation of Protein B23 during Programmed Cell Death in the Prostate Gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Translocation of nucleolar phosphoprotein B23 (37 kDa/pI 5.1) induced by selective inhibitors of ribosome synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Hot on the TRAIL of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Localization of NuMA protein isoforms in the nuclear matrix of mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204766

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204766

1 reference

Dimensions Publication ID

2 August 2017

1019863003

0 references

1 reference