Functional heavy-chain antibodies in Camelidae (Q34419540)

2 August 2017

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title

Functional heavy-chain antibodies in Camelidae (English)

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2 August 2017

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Camelidae

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Nguyen VK

1

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2 August 2017

Desmyter A

series ordinal

2

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2 August 2017

Muyldermans S

series ordinal

3

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2 August 2017

publication date

1 January 2001

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2 August 2017

published in

Advances in Immunology

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2 August 2017

volume

79

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2 August 2017

page(s)

261-296

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Standard conformations for the canonical structures of immunoglobulins

2 August 2017

cites work

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The differences between the structural repertoires of VH germ-line gene segments of mice and humans: implication for the molecular mechanism of the immune response

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Immunoglobulins of camel (Camelus dromedarius) colostrum

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Use of antibody fragments in immunoaffinity chromatography. Comparison of FV fragments, VH fragments and paralog peptides

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7 January 2021

Karyological conservatism in South American camelids

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Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.

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7 January 2021

Antibodies in diagnostics - from immunoassays to protein chips

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7 January 2021

Canonical structures for the hypervariable regions of immunoglobulins

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7 January 2021

Conformations of immunoglobulin hypervariable regions

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7 January 2021

Structural repertoire of the human VH segments

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7 January 2021

Immunoglobulin gene alterations in human heavy chain diseases.

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7 January 2021

The human immunoglobulin VH repertoire

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7 January 2021

'Camelising' human antibody fragments: NMR studies on VH domains.

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7 January 2021

Antibody VH domains as small recognition units

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7 January 2021

Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability

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7 January 2021

Selection of high-affinity phage antibodies from phage display libraries

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7 January 2021

Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire

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7 January 2021

Antibody arrays for high-throughput screening of antibody-antigen interactions

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7 January 2021

A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?

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7 January 2021

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

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7 January 2021

Sequence-imposed structural constraints in the TonB protein of E. coli.

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7 January 2021

Three-dimensional structure of an Fv from a human IgM immunoglobulin

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7 January 2021

Kinetic maturation of an immune response

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Isolation of antigen specific llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Clinical trials of antibody therapy

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

A comparison of strategies to stabilize immunoglobulin Fv-fragments

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Naturally occurring antibodies devoid of light chains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Comparison of intact antibody structures and the implications for effector function.

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Mix and match: building manifold binding sites

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Natural and designer binding sites made by phage display technology

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Antibody phage display technology and its applications.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Development and application of cytotoxic T lymphocyte-associated antigen 4 as a protein scaffold for the generation of novel binding ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Nucleotide sequences and expression of cDNAs for a bovine anti-testosterone monoclonal IgG1 antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

BiP binding sequences in antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Restricted VH gene usage and generation of antibody diversity in rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

The fibronectin type III domain as a scaffold for novel binding proteins

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Elbow motion in the immunoglobulins involves a molecular ball-and-socket joint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

The atomic structure of protein-protein recognition sites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

A single VH family and long CDR3s are the targets for hypermutation in bovine immunoglobulin heavy chains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Affinity selection of a camelized V(H) domain antibody inhibitor of hepatitis C virus NS3 protease

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Tendamistat as a scaffold for conformationally constrained phage peptide libraries

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7 January 2021

Roles of IgH and L chains and of surrogate H and L chains in the development of cells of the B lymphocyte lineage

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https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

The specific variable domain of camel heavy-chain antibodies is encoded in the germline

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Immunoglobulin VH domains and beyond: design and selection of single-domain binding and targeting reagents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Evolution of immunoglobulin VH pseudogenes in chickens

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Anatomy of the antibody molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Identification of specificity-determining residues in antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

The hydrolysis of rabbit y-globulin and antibodies with crystalline papain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Conservation of sequence in recombination signal sequence spacers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Distinct patterns of IgH structure and organization in a divergent lineage of chrondrichthyan fishes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

An antibody single-domain phage display library of a native heavy chain variable region: isolation of functional single-domain VH molecules with a unique interface.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Somatic hyperconversion diversifies the single Vh gene of the chicken with a high incidence in the D region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Single domain antibodies: comparison of camel VH and camelised human VH domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Procyclin gene expression and loss of the variant surface glycoprotein during differentiation of Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Intracellular antibodies (intrabodies) for gene therapy of infectious diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

A single predominantly expressed polymorphic immunoglobulin VH gene family, related to mammalian group, I, clan, II, is identified in cattle.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Exceptionally long CDR3H region with multiple cysteine residues in functional bovine IgM antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Structure and evolution of mammalian VH families

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Heavy Chain Diseases: Current Findings and Concepts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Redefining the minimal antigen-binding fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Camelid heavy-chain variable domains provide efficient combining sites to haptens

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Uniformity of karyotypes in the Camelidae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Induction of immune responses and molecular cloning of the heavy chain antibody repertoire of Lama glama

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Comparison of llama VH sequences from conventional and heavy chain antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Making antibodies by phage display technology

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

The structure of the llama heavy chain constant genes reveals a mechanism for heavy-chain antibody formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

Length distribution of CDRH3 in antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

X-ray crystallography of antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979006-2

7 January 2021

10.1016/S0065-2776(01)79006-2

Identifiers

DOI

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2 August 2017

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