Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. (Q34346883)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18371452%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo (English)

1 reference

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4 January 2020

1 reference

Heather E Fleming

1

1 reference

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4 January 2020

Viktor Janzen

2

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4 January 2020

Jun Guo

4

1 reference

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4 January 2020

Kathleen M Leahy

5

1 reference

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4 January 2020

Henry M Kronenberg

6

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4 January 2020

language of work or name

English

0 references

publication date

1 March 2008

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4 January 2020

1 reference

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4 January 2020

volume

2

1 reference

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4 January 2020

issue

3

1 reference

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4 January 2020

page(s)

274-283

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Limiting factors in murine hematopoietic stem cell assays.

4 January 2020

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

6 July 2018

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Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

6 July 2018

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HOXB4-induced self-renewal of hematopoietic stem cells is significantly enhanced by p21 deficiency

6 July 2018

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6 July 2018

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Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

6 July 2018

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Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

6 July 2018

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DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway

6 July 2018

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Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

6 July 2018

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Osteoblastic cells regulate the haematopoietic stem cell niche

6 July 2018

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6 July 2018

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

6 July 2018

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

6 July 2018

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Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo.

6 July 2018

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Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

6 July 2018

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HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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27 October 2018

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Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

27 October 2018

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HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding

27 October 2018

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p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity

27 October 2018

1 reference

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Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

27 October 2018

1 reference

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Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

27 October 2018

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Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6.

27 October 2018

1 reference

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HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors.

27 October 2018

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Expression pattern of Dkk-1 during mouse limb development.

27 October 2018

1 reference

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Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

27 October 2018

1 reference

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Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

27 October 2018

1 reference

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Phenotypic and functional changes induced at the clonal level in hematopoietic stem cells after 5-fluorouracil treatment

27 October 2018

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12 December 2020

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

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12 December 2020

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

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12 December 2020

Therapeutic targeting of a stem cell niche

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12 December 2020

Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis

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12 December 2020

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin

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12 December 2020

Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases

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12 December 2020

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

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12 December 2020

10.1016/J.STEM.2008.01.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18371452%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18371452%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18371452

1 reference