Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. (Q34336896)

1 August 2017

title

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. (English)

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1 August 2017

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Andoh T

1

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1 August 2017

Ishii K

2

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1 August 2017

Suzuki Y

3

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1 August 2017

Ikegami Y

4

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1 August 2017

Kusunoki Y

5

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1 August 2017

Takemoto Y

6

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1 August 2017

Okada K

7

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1 August 2017

language of work or name

English

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publication date

1 August 1987

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

84

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1 August 2017

issue

16

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1 August 2017

page(s)

5565-5569

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describes a project that uses

1 August 2017

CPT-K5

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cites work

DNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA.

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A site and strand spedfic nuciease activity with analogies to topoisomerase I frames the rRNA gene ofTetrahymena

6 July 2018

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Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins

6 July 2018

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Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins.

6 July 2018

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Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases

6 July 2018

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6 July 2018

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Escherichia coli and Salmonella typhimurium supX genes specify deoxyribonucleic acid topoisomerase I

6 July 2018

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Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition

6 July 2018

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DNA Gyrase and the Supercoiling of DNA

6 July 2018

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Properties of active nucleosomes as revealed by HMG 14 and 17 chromatography.

6 July 2018

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Immunoblotting and dot immunobinding — Current status and outlook

6 July 2018

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Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome

6 July 2018

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Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization

6 July 2018

1 reference

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Ribosome Formation is Blocked by Camptothecin, a Reversible Inhibitor of RNA Synthesis

6 July 2018

1 reference

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Intracellular degradation of HeLa and adenovirus type 2 DNA induced by camptothecin

6 July 2018

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Camptothecin inhibits macromolecular synthesis in mammalian cells but not in isolated mitochondria or lE. coli

6 July 2018

1 reference

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Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880).

6 July 2018

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Selective interruption of high molecular weight RNA synthesis in HeLa cells by camptothecin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298903

Mechanism of inhibition of mammalian DNA topoisomerase I by heparin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298903

Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298903

Topoisomerase I has a strong binding preference for a conserved hexadecameric sequence in the promoter region of the rRNA gene from Tetrahymena pyriformis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298903

A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

6 July 2018

1 reference

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Proteins that Affect DNA Conformation

6 July 2018

1 reference

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Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298903

Lethal activity of camptothecin sodium on human lymphoma cells.

27 October 2018

1 reference

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Effects of camptothecin on RNA synthesis in leukemia L1210 cells

27 October 2018

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12 December 2020

Studies on camptothecin-induced degradation and apparent reaggregation of DNA from L1210 cells

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12 December 2020

Action of camptothecin on mammalian cells in culture

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12 December 2020

Inhibition of topoisomerase I by heparin

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12 December 2020

Escherichia coli DNA topoisomerase I mutants: Increased supercoiling is corrected by mutations near gyrase genes

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12 December 2020

Regulation of DNA Supercoiling in Escherichia coli

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12 December 2020

Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling

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12 December 2020

Cytotoxicity and sister chromatid exchanges induced in vitro by six anticancer drugs developed in the People's Republic of China

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12 December 2020

Rapid purification and characterization of DNA topoisomerase I from cultured mouse mammary carcinoma FM3A cells

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12 December 2020

Identification of Saccharomyces cerevisiae mutants deficient in DNA topoisomerase I activity

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12 December 2020

DNA topoisomerase I and II activities during cell proliferation and the cell cycle in cultured mouse embryo fibroblast (C3H 10T1/2) cells

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12 December 2020

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12 December 2020

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

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12 December 2020

A quantitative decatenation assay for type II topoisomerases

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12 December 2020

Identifiers

DOI

10.1073/PNAS.84.16.5565

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1 August 2017

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1 August 2017

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