The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. (Q34328370)

1 August 2017

title

The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. (English)

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1 August 2017

2

Alexandra C Newton

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1 August 2017

Charles C King

1

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1 August 2017

language of work or name

English

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publication date

21 June 2004

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

279

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1 August 2017

issue

36

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1 August 2017

page(s)

37518-37527

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Three protein kinase structures define a common motif

1 August 2017

cites work

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21 January 2018

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21 January 2018

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21 January 2018

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Human growth factor receptor bound 14 binds the activated insulin receptor and alters the insulin-stimulated tyrosine phosphorylation levels of multiple proteins

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes

21 January 2018

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

21 January 2018

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The carboxyl terminus of protein kinase c provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1.

21 January 2018

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Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

21 January 2018

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The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta

21 January 2018

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

21 January 2018

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Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice

21 January 2018

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Role for the adaptor protein Grb10 in the activation of Akt

21 January 2018

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Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor

21 January 2018

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Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

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Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M405340200

1 reference

1 August 2017

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