The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor (Q34318688)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15126507%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor (English)

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28 December 2019

5

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28 December 2019

author name string

Virginie Binet

1

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28 December 2019

Carole Brajon

2

1 reference

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28 December 2019

Laurent Le Corre

3

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28 December 2019

Francine Acher

4

1 reference

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28 December 2019

Laurent Prézeau

6

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28 December 2019

language of work or name

English

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publication date

4 May 2004

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Journal of Biological Chemistry

28 December 2019

published in

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28 December 2019

volume

279

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28 December 2019

issue

28

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28 December 2019

page(s)

29085-29091

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Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

28 December 2019

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No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.

6 July 2018

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Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors

6 July 2018

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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

6 July 2018

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Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501

6 July 2018

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Activation of rhodopsin: new insights from structural and biochemical studies

6 July 2018

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Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding

6 July 2018

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Role of heteromer formation in GABAB receptor function

6 July 2018

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6 July 2018

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Heterodimerization is required for the formation of a functional GABA(B) receptor

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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21 January 2018

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Cell surface detection of membrane protein interaction with homogeneous time-resolved fluorescence resonance energy transfer technology

21 January 2018

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Mutational analysis and molecular modeling of the allosteric binding site of a novel, selective, noncompetitive antagonist of the metabotropic glutamate 1 receptor

21 January 2018

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Importance of the gamma-aminobutyric acid(B) receptor C-termini for G-protein coupling.

21 January 2018

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Biophysics: is rhodopsin dimeric in native retinal rods?

21 January 2018

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Positive allosteric modulators for gamma-aminobutyric acid(B) receptors open new routes for the development of drugs targeting family 3 G-protein-coupled receptors

28 October 2018

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The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues

28 October 2018

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12 December 2020

The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

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12 December 2020

GABA(B2) is essential for g-protein coupling of the GABA(B) receptor heterodimer

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12 December 2020

A model for the functioning of family 3 GPCRs

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12 December 2020

Identifiers

DOI

10.1074/JBC.M400930200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15126507%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15126507%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

PubMed publication ID

15126507

1 reference