Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis (Q34315290)

1 August 2017

1 reference

title

Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis (English)

1 reference

1 August 2017

Christian Beyer

1

1 reference

1 August 2017

Clara Dees

series ordinal

2

1 reference

1 August 2017

Jörg H W Distler

series ordinal

3

1 reference

1 August 2017

publication date

4 December 2012

1 reference

Archives of Dermatological Research

1 August 2017

published in

1 reference

1 August 2017

volume

305

1 reference

1 August 2017

issue

1

1 reference

1 August 2017

page(s)

1-8

1 reference

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Notch signaling: simplicity in design, versatility in function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Innovative antifibrotic therapies in systemic sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Canonical and non-canonical Notch ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Notch signaling: the core pathway and its posttranslational regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Hedgehog morphogen: from secretion to reception

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Wnt/beta-catenin signaling promotes renal interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Gli proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Mechanisms and functions of Hedgehog signalling across the metazoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Selective activation mechanisms of Wnt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Wnt/beta-catenin signaling: components, mechanisms, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Three decades of Wnts: a personal perspective on how a scientific field developed

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Drugging Wnt signalling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Strategies for homeostatic stem cell self-renewal in adult tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Notch in the kidney: development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Changes in causes of death in systemic sclerosis, 1972-2002

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

The many faces and functions of β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Systemic sclerosis: a prototypic multisystem fibrotic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

Targeting ADAM-17/notch signaling abrogates the development of systemic sclerosis in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00403-012-1304-7

10.1007/S00403-012-1304-7

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

1 August 2017

1032267550

0 references

1 reference