HTLV-I Tax related dysfunction of cell cycle regulators and oncogenesis of adult T cell leukemia (Q34293483)

1 August 2017

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title

HTLV-I Tax related dysfunction of cell cycle regulators and oncogenesis of adult T cell leukemia (English)

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Human T-lymphotropic virus 1

1 August 2017

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1 reference

Arima N

1

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1 August 2017

Tei C

series ordinal

2

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1 August 2017

publication date

1 January 2001

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1 August 2017

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1 August 2017

volume

40

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1 August 2017

issue

3-4

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1 August 2017

page(s)

267-278

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

1 August 2017

cites work

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21 January 2018

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A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus

21 January 2018

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HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

21 January 2018

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HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.

21 January 2018

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Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

21 January 2018

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c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I

21 January 2018

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Human adult T-cell leukemia virus: molecular cloning of the provirus DNA and the unique terminal structure

21 January 2018

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The x gene is essential for HTLV replication

21 January 2018

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Expression of the pX gene of HTLV-I: general splicing mechanism in the HTLV family

21 January 2018

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Transcriptional (p40x) and post-transcriptional (p27x-III) regulators are required for the expression and replication of human T-cell leukemia virus type I genes

21 January 2018

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Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.

21 January 2018

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Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

21 January 2018

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

Pro-inflammatory signaling: last pieces in the NF-kappaB puzzle?

21 January 2018

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https://api.crossref.org/works/10.3109%2F10428190109057925

The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

NF-kappaB involvement in the activation of primary adult T-cell leukemia cells and its clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Checkpoints: controls that ensure the order of cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

G1 phase progression: cycling on cue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Localization of a tumor suppressor gene in 11p15.5 using the G401 Wilms' tumor assay

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A cell cycle regulator potentially involved in genesis of many tumor types

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Mutations and altered expression of p16INK4 in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Cell-cycle regulators and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Analysis of p18INK4C in adult T‐cell leukaemia and non‐Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Mutations of the INK4a locus in squamous cell carcinomas of human skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

An imprinted gene p57KIP2 is mutated in Beckwith-Wiedemann syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A novel cyclin encoded by a bcl1-linked candidate oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Inactivation of the retinoblastoma susceptibility gene in human breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Down-regulation of the INK4 family of cyclin-dependent kinase inhibitors by tax protein of HTLV-1 through two distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Multi-step carcinogenesis model for adult T-cell leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Trans-activator Tax of human T-cell leukemia virus type 1 enhances mutation frequency of the cellular genome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10428190109057925

10.3109/10428190109057925

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference