Kinase suppressor of Ras 1 is required for full ERK activation in thymocytes but not for thymocyte selection. (Q34293064)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20865788%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Kinase suppressor of Ras 1 is required for full ERK activation in thymocytes but not for thymocyte selection (English)

1 reference

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14 February 2020

0 references

3

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14 February 2020

Yina H Huang

5

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14 February 2020

author name string

Erin L Filbert

1

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14 February 2020

Anhco Nguyen

2

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14 February 2020

B J Fowlkes

4

1 reference

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14 February 2020

Andrey S Shaw

6

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14 February 2020

language of work or name

English

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publication date

24 September 2010

1 reference

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14 February 2020

number of pages

9

1 reference

European Journal of Immunology

inferred from page(s)

published in

1 reference

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14 February 2020

volume

40

1 reference

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14 February 2020

issue

11

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14 February 2020

page(s)

3226-3234

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Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells

14 February 2020

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Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

6 July 2018

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The why and how of thymocyte negative selection

6 July 2018

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A requirement for sustained ERK signaling during thymocyte positive selection in vivo

6 July 2018

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A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

6 July 2018

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RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.

6 July 2018

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Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

6 July 2018

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

6 July 2018

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Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

6 July 2018

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Signals involved in thymocyte positive and negative selection

6 July 2018

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The Influence of the MAPK Pathway on T Cell Lineage Commitment

6 July 2018

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Positive and negative selection invoke distinct signaling pathways.

6 July 2018

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The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

6 July 2018

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The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

6 July 2018

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KSR, a novel protein kinase required for RAS signal transduction

6 July 2018

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The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions.

6 July 2018

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Involvement of p21ras distinguishes positive and negative selection in thymocytes

6 July 2018

1 reference

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Positive selection of thymocytes

6 July 2018

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Positive and negative selection of an antigen receptor on T cells in transgenic mice.

6 July 2018

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

6 July 2018

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

6 July 2018

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Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules

6 July 2018

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In vivo and in vitro clonal deletion of double-positive thymocytes

6 July 2018

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MEK activity regulates negative selection of immature CD4+CD8+ thymocytes

6 July 2018

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Crossref

https://api.crossref.org/works/10.1002%2FEJI.201040349

Kinase suppressor of Ras couples Ras to the ERK cascade during T cell development

21 January 2018

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Crossref

https://api.crossref.org/works/10.1002%2FEJI.201040349

Negative selection of the T-cell repertoire: where and when does it occur?

21 January 2018

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28 October 2018

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The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis

28 October 2018

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Duration of calcineurin and Erk signals regulates CD4/CD8 lineage commitment of thymocytes

28 October 2018

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C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation

28 October 2018

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Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage commitment in the thymus.

28 October 2018

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Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

28 October 2018

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MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent

28 October 2018

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Selective requirement for MAP kinase activation in thymocyte differentiation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976810

Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

28 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FEJI.201040349

The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20865788

12 December 2020

inferred from PubMed ID database lookup

Degree of ERK activation influences both positive and negative thymocyte selection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20865788

12 December 2020

inferred from PubMed ID database lookup

Raf regulates positive selection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20865788

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/EJI.201040349

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20865788%20AND%20SRC:MED&resulttype=core&format=json

release_spi6o6gzjrhr7fgdtzyosfl2ku

14 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/spi6o6gzjrhr7fgdtzyosfl2ku

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20865788%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

20865788

1 reference