Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade (Q34281252)

1 August 2017

title

Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade (English)

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1 August 2017

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17

Michael Karin

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1 August 2017

3

Joan Font-Burgada

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Li-Wha Wu

object named as

Li-Wha Wu

12

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Michael Poidinger

object named as

Michael Poidinger

7

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Tannishtha Reya

16

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Subhra K Biswas

6

object named as

Subhra K Biswas

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1 August 2017

Xuefeng Wu

1

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1 August 2017

Weizhou Zhang

2

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1 August 2017

Trenis Palmer

4

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1 August 2017

Alexander S Hamil

5

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1 August 2017

Nicholas Borcherding

8

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1 August 2017

Qing Xie

9

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1 August 2017

Lesley G Ellies

10

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1 August 2017

Nikki K Lytle

11

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1 August 2017

Raymond G Fox

13

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1 August 2017

Jing Yang

14

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Steven F Dowdy

15

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1 August 2017

language of work or name

English

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publication date

4 September 2014

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

111

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1 August 2017

issue

38

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1 August 2017

page(s)

13870-13875

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183333

1 August 2017

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Attenuation of TGF-β signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model

6 July 2018

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Tumor metastasis: moving new biological insights into the clinic

6 July 2018

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6 July 2018

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Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK.

6 July 2018

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6 July 2018

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TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis

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EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis

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6 July 2018

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HGFK1 inhibits bone metastasis in breast cancer through the TAK1/p38 MAPK signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183333

Roles of p38 MAPKs in invasion and metastasis

6 July 2018

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Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs.

6 July 2018

1 reference

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Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain.

6 July 2018

1 reference

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ERK1/2 and p38α/β signaling in tumor cell quiescence: opportunities to control dormant residual disease

6 July 2018

1 reference

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D2-40: an additional marker for myoepithelial cells of breast and the precaution in interpreting tumor lymphovascular invasion

6 July 2018

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Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling

6 July 2018

1 reference

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6 July 2018

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TGF- Biology in Mammary Development and Breast Cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183333

Mechanisms and functions of p38 MAPK signalling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183333

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183333

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

6 July 2018

1 reference

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The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer

6 July 2018

1 reference

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Control of p53 multimerization by Ubc13 is JNK-regulated

6 July 2018

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Signal integration by JNK and p38 MAPK pathways in cancer development

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Ubiquitylation in innate and adaptive immunity.

6 July 2018

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Regulatory ubiquitylation in response to DNA double-strand breaks

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6 July 2018

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TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

6 July 2018

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

6 July 2018

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6 July 2018

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IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

6 July 2018

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6 July 2018

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TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.

6 July 2018

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IGFBP3 mRNA expression in benign and malignant breast tumors

6 July 2018

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6 July 2018

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MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer

6 July 2018

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6 July 2018

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StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.

6 July 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

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p38 MAP kinases: beyond the stress response

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

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Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex

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Expressions of transforming growth factor (TGF)-beta1 and TGF-beta type II receptor and their relationship with apoptosis during chemical hepatocarcinogenesis in rats.

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SnapShot: p38 MAPK signaling.

21 January 2018

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Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

21 January 2018

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TGF-beta 1 causes increased endothelial ICAM-1 expression and lung injury

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25189770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25189770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25189770

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1414358111

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference