Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function (Q34265770)

1 August 2017

title

Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function (English)

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1 August 2017

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Anne Bugge

1

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ORCID Public Data File 2021

author name string

Dan Feng

2

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1 August 2017

Logan J Everett

3

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1 August 2017

Erika R Briggs

4

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1 August 2017

Shannon E Mullican

5

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1 August 2017

Fenfen Wang

6

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1 August 2017

Jennifer Jager

7

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1 August 2017

Mitchell A Lazar

8

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1 August 2017

publication date

1 April 2012

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1 August 2017

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1 August 2017

volume

26

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1 August 2017

issue

7

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1 August 2017

page(s)

657-667

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Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

1 August 2017

cites work

1 reference

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Circadian Epigenomic Remodeling and Hepatic Lipogenesis: Lessons from HDAC3

6 July 2018

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Circadian rhythms, sleep, and metabolism

6 July 2018

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A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

6 July 2018

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Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages

6 July 2018

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Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REV-ERB.

6 July 2018

1 reference

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Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance

6 July 2018

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Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene

6 July 2018

1 reference

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GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα

6 July 2018

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E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha

6 July 2018

1 reference

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

6 July 2018

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Regulation of adipogenesis by natural and synthetic REV-ERB ligands.

6 July 2018

1 reference

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Circadian clock gene Bmal1 is not essential; functional replacement with its paralog, Bmal2.

6 July 2018

1 reference

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Metabolism and cancer: the circadian clock connection

6 July 2018

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REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis

6 July 2018

1 reference

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The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

6 July 2018

1 reference

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An integrated software system for analyzing ChIP-chip and ChIP-seq data

6 July 2018

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The genetics of mammalian circadian order and disorder: implications for physiology and disease

6 July 2018

1 reference

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Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Divergent metabolic adaptations to intestinal parasitic nematode infection in mice susceptible or resistant to obesity

6 July 2018

1 reference

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Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Structural insight into the constitutive repression function of the nuclear receptor Rev-erbbeta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Interplay of circadian clocks and metabolic rhythms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery

6 July 2018

1 reference

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Nuclear receptor corepressors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Rev-erbbeta regulates the expression of genes involved in lipid absorption in skeletal muscle cells: evidence for cross-talk between orphan nuclear receptors and myokines

6 July 2018

1 reference

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BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The mammalian circadian timing system: from gene expression to physiology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The role of corepressors in transcriptional regulation by nuclear hormone receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Daily rhythms in glucose metabolism: suprachiasmatic nucleus output to peripheral tissue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Coordinated transcription of key pathways in the mouse by the circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The orphan receptor Rev-ErbA alpha activates transcription via a novel response element

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Rev-erb beta, a new member of the nuclear receptor superfamily, is expressed in the nervous system during chicken development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Separate and overlapping metabolic functions of LXRalpha and LXRbeta in C57Bl/6 female mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Shift work and metabolic syndrome: respective impacts of job strain, physical activity, and dietary rhythms

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323877

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22474260

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Circadian changes in serum and liver metabolites and liver lipogenic enzymes in ad libitum- and meal-fed, lean and obese Zucker rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22474260

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.186858.112

1 reference

1 August 2017

1 reference

1 August 2017

1 reference