Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway. (Q34146539)

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14 February 2020

title

Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway (English)

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14 February 2020

7

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1

Wenwei Hu

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14 February 2020

8

Arnold J Levine

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4

David S Klimstra

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2

Zhaohui Feng

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14 February 2020

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Ippolito Modica

3

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Lin Song

series ordinal

5

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Peter J Allen

series ordinal

6

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Laura H Tang

series ordinal

9

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publication date

1 May 2010

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14 February 2020

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14 February 2020

volume

1

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issue

4

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14 February 2020

page(s)

360-368

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Progress in the treatment of neuroendocrine tumors

14 February 2020

cites work

1 reference

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The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop

5 July 2018

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5 July 2018

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A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells

5 July 2018

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A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans

5 July 2018

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Rare tumors of the colon and rectum: a national review

5 July 2018

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The P53 pathway: what questions remain to be explored?

5 July 2018

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Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

5 July 2018

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Endocrine tumours of the pancreas

5 July 2018

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The p53 pathway: positive and negative feedback loops

5 July 2018

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MDM2 is a central node in the p53 pathway: 12 years and counting

5 July 2018

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A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

5 July 2018

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TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer

5 July 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

5 July 2018

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General keynote: hereditary cancer: lessons from Li-Fraumeni syndrome

5 July 2018

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5 July 2018

Surfing the p53 network

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Molecular genetics of neuroendocrine tumors

5 July 2018

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Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms

5 July 2018

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5 July 2018

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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

5 July 2018

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

5 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

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5 July 2018

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12 December 2020

Midgut Carcinoids and Solid Carcinomas of the Intestine: Differences in Endocrine Markers and p53 Mutations

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12 December 2020

Carcinoid tumors frequently display genetic abnormalities involving chromosome 11

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12 December 2020

Molecular genetics of neuroendocrine tumors

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12 December 2020

Identification of p53 gene mutations in gastrointestinal and pancreatic carcinoids by nonradioisotopic SSCA

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12 December 2020

Identifiers

DOI

10.1177/1947601910371979

1 reference

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14 February 2020

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14 February 2020

PubMed publication ID

20871795

1 reference