Mechanisms of angiogenesis and their use in the inhibition of tumor growth and metastasis. (Q34130552)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11156525%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

review article

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title

Mechanisms of angiogenesis and their use in the inhibition of tumor growth and metastasis (English)

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3 November 2019

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3

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3 November 2019

author name string

Saaristo A

series ordinal

1

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3 November 2019

Karpanen T

series ordinal

2

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3 November 2019

language of work or name

English

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publication date

1 December 2000

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3 November 2019

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3 November 2019

volume

19

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3 November 2019

issue

53

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3 November 2019

page(s)

6122-6129

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Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

3 November 2019

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VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Induction of angiogenesis during the transition from hyperplasia to neoplasia

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Angiogenesis in cancer, vascular, rheumatoid and other disease

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The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin.

21 January 2018

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Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

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Hypoxia and the regulation of gene expression

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Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

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Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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Openings between defective endothelial cells explain tumor vessel leakiness

21 January 2018

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Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

21 January 2018

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Antiangiogenis restricted tumor dormancy

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Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

21 January 2018

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Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

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Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

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Proteolytic processing regulates receptor specificity and activity of VEGF-C

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A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities

21 January 2018

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Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a.

21 January 2018

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Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

21 January 2018

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Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema

21 January 2018

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Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents

21 January 2018

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Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3

21 January 2018

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

21 January 2018

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Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin

21 January 2018

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Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

21 January 2018

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Tumor targeting with a selective gelatinase inhibitor

21 January 2018

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Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor

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Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

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A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

21 January 2018

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

21 January 2018

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Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites

21 January 2018

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VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours.

21 January 2018

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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

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21 January 2018

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Antiangiogenic activity of the cleaved conformation of the serpin antithrombin

21 January 2018

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A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

21 January 2018

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Impact of oncogenes in tumor angiogenesis: Mutant K- ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

21 January 2018

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21 January 2018

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Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment

21 January 2018

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

21 January 2018

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Mechanisms of angiogenesis

21 January 2018

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21 January 2018

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21 January 2018

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Vascular endothelial growth factor-C and its receptor VEGFR-3 in the nasal mucosa and in nasopharyngeal tumors

21 January 2018

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

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Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

21 January 2018

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21 January 2018

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Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon

21 January 2018

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21 January 2018

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Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

21 January 2018

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Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

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The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

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A cancer therapy resistant to resistance

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Chemotherapy targeted to tumor vasculature.

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7 January 2021

Angiogenesis as a marker of preneoplastic lesions of the human breast

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction.

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Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma

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Basement Membrane Collagen: Degradation by Migrating Endothelial Cells

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During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium

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Neuropilin-1 is a placenta growth factor-2 receptor

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Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition

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Vascular endothelial growth factor (VEGF) and its receptors

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The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

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7 January 2021

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

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7 January 2021

Vascular gene transfer

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203969

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11156525%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 November 2019

1034156048

0 references

1 reference