Bactericidal activities of BMS-284756, a novel Des-F(6)-quinolone, against Staphylococcus aureus strains with topoisomerase mutations (Q34104362)

31 July 2017

title

Bactericidal activities of BMS-284756, a novel Des-F(6)-quinolone, against Staphylococcus aureus strains with topoisomerase mutations (English)

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31 July 2017

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Staphylococcus aureus

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Laura E Lawrence

1

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31 July 2017

MaryBeth Frosco

2

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31 July 2017

Brenda Ryan

3

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31 July 2017

Susan Chaniewski

4

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31 July 2017

Hyekyung Yang

5

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31 July 2017

David C Hooper

6

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31 July 2017

John F Barrett

7

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31 July 2017

language of work or name

English

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publication date

1 January 2002

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Antimicrobial Agents and Chemotherapy

31 July 2017

published in

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31 July 2017

volume

46

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31 July 2017

issue

1

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31 July 2017

page(s)

191-195

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Staphylococcus aureus mutants selected by BMS-284756.

31 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

Selection and genetic characterization of Streptococcus pneumoniae mutants resistant to the des-F(6) quinolone BMS-284756.

5 July 2018

1 reference

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Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

Potent antipneumococcal activity of gemifloxacin is associated with dual targeting of gyrase and topoisomerase IV, an in vivo target preference for gyrase, and enhanced stabilization of cleavable complexes in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

Primary targets of fluoroquinolones in Streptococcus pneumoniae.

5 July 2018

1 reference

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Mutations in Topoisomerase IV and DNA Gyrase of Staphylococcus aureus : Novel Pleiotropic Effects on Quinolone and Coumarin Activity

5 July 2018

1 reference

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Increased expression of fibronectin-binding proteins by fluoroquinolone-resistant Staphylococcus aureus exposed to subinhibitory levels of ciprofloxacin.

5 July 2018

1 reference

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Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones.

5 July 2018

1 reference

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Quinolone resistance mutations in topoisomerase IV: relationship to the flqA locus and genetic evidence that topoisomerase IV is the primary target and DNA gyrase is the secondary target of fluoroquinolones in Staphylococcus aureus.

5 July 2018

1 reference

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Quinolone resistance mediated by norA: physiologic characterization and relationship to flqB, a quinolone resistance locus on the Staphylococcus aureus chromosome

5 July 2018

1 reference

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Structure-activity and structure-side-effect relationships for the quinolone antibacterials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

Bacterial resistance to fluoroquinolones: lessons to be learned

5 July 2018

1 reference

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Chemotherapeutic activity of levofloxacin (HR 355, DR-3355) against systemic and localized infections in laboratory animals

5 July 2018

1 reference

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Confirmation of protoplast fusion-derived linkages in Staphylococcus aureus by transformation with protoplast DNA.

5 July 2018

1 reference

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The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

Postantibiotic effect of DU-6859a and levofloxacin as compared with ofloxacin.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126973

10.1128/AAC.46.1.191-195.2002

28 October 2018

Identifiers

DOI

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31 July 2017

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31 July 2017

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