The immunosuppressant FTY720 (fingolimod) enhances glycosaminoglycan depletion in articular cartilage (Q34094557)

31 July 2017

title

The immunosuppressant FTY720 (fingolimod) enhances glycosaminoglycan depletion in articular cartilage (English)

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31 July 2017

1 reference

1 reference

Winfried B. Graninger

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author name string

Martin H Stradner

1

1 reference

31 July 2017

Hannes Angerer

2

1 reference

31 July 2017

Thomas Ortner

3

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31 July 2017

Florentine C Fuerst

4

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31 July 2017

Daniela Setznagl

5

1 reference

31 July 2017

Marie-Luise Kremser

6

1 reference

31 July 2017

Josef Hermann

7

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31 July 2017

Winfried B Graninger

8

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31 July 2017

publication date

12 December 2011

1 reference

BMC Musculoskeletal Disorders

31 July 2017

published in

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31 July 2017

volume

12

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31 July 2017

page(s)

279

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MIQE précis: Practical implementation of minimum standard guidelines for fluorescence-based quantitative real-time PCR experiments

31 July 2017

cites work

1 reference

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Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model

5 July 2018

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Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.

5 July 2018

1 reference

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

5 July 2018

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A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

5 July 2018

1 reference

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"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets

5 July 2018

1 reference

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Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes

5 July 2018

1 reference

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

5 July 2018

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

5 July 2018

1 reference

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Primer3 on the WWW for general users and for biologist programmers

5 July 2018

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Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target

5 July 2018

1 reference

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Chondrocyte apoptosis induced by nitric oxide

5 July 2018

1 reference

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FTY720 versus mycophenolate mofetil in de novo renal transplantation: six-month results of a double-blind study

5 July 2018

1 reference

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FTY720: dissection of membrane receptor-operated, stereospecific effects on cell migration from receptor-independent antiproliferative and apoptotic effects

21 January 2018

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S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis

21 January 2018

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Reduction of CD4 positive T cells and improvement of pathological changes of collagen-induced arthritis by FTY720.

21 January 2018

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Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes.

21 January 2018

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Sphingosine-1-phosphate stimulates rat primary chondrocyte proliferation.

21 January 2018

1 reference

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A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures

21 January 2018

1 reference

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Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses

21 January 2018

1 reference

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Activation of stress-activated protein kinase in osteoarthritic cartilage: evidence for nitric oxide dependence

21 January 2018

1 reference

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Animal models of arthritis in NOS2-deficient mice.

21 January 2018

1 reference

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Preparation of antibodies against a novel immunosuppressant, FTY720, and development of an enzyme immunoassay for FTY720.

21 January 2018

1 reference

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The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

21 January 2018

1 reference

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Limitations of safranin 'O' staining in proteoglycan-depleted cartilage demonstrated with monoclonal antibodies

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22151889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of interleukin 1 and leukaemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22151889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of FTY720, a novel immunosuppressant, on adjuvant- and collagen-induced arthritis in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22151889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2474-12-279

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

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