Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment (Q34093086)

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9 February 2020

title

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment (English)

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9 February 2020

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5

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9 February 2020

Wilco de Jager

6

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9 February 2020

Mona Bajaj-Elliott

9

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9 February 2020

Lucy R Wedderburn

10

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9 February 2020

8

Rolando Cimaz

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9 February 2020

author name string

Kiran Nistala

1

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9 February 2020

Stuart Adams

2

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9 February 2020

Helen Cambrook

3

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9 February 2020

Simona Ursu

4

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9 February 2020

Jamie G Evans

7

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9 February 2020

language of work or name

English

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publication date

2 August 2010

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Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

published in

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9 February 2020

volume

107

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9 February 2020

issue

33

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9 February 2020

page(s)

14751-14756

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T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

9 February 2020

cites work

1 reference

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In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

5 July 2018

1 reference

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C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

5 July 2018

1 reference

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

5 July 2018

1 reference

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Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

5 July 2018

1 reference

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Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

5 July 2018

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5 July 2018

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Late developmental plasticity in the T helper 17 lineage

5 July 2018

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Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis

5 July 2018

1 reference

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Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma

5 July 2018

1 reference

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Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

5 July 2018

1 reference

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PILAR is a novel modulator of human T-cell expansion

5 July 2018

1 reference

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The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

Rapid ex vivo isolation and long-term culture of human Th17 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

Phenotypic and functional features of human Th17 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930428

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

5 July 2018

1 reference

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Brn-3a neuronal transcription factor functional expression in human prostate cancer

5 July 2018

1 reference

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

5 July 2018

1 reference

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International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001

5 July 2018

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

5 July 2018

1 reference

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IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

5 July 2018

1 reference

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

5 July 2018

1 reference

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NKR-P1, a signal transduction molecule on natural killer cells

5 July 2018

1 reference

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CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003852107

Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003852107

Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003852107

Molecular fingerprinting reveals non-overlapping T cell oligoclonality between an inflamed site and peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003852107

The role of retinoic acid-related orphan receptor variant 2 and IL-17 in the development and function of human CD4+ T cells.

21 January 2018

1 reference

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Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in rheumatoid arthri

21 January 2018

1 reference

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The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4

21 January 2018

1 reference

12 December 2020

Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides

1 reference

12 December 2020

Autoimmunity: increasing suspects in the CD4+ T cell lineup

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12 December 2020

Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis

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12 December 2020

IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells

1 reference

12 December 2020

Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies

1 reference

12 December 2020

Selective recruitment of polarized T cells expressing CCR5 and CXCR3 to the inflamed joints of children with juvenile idiopathic arthritis

1 reference

12 December 2020

Clonal evolution of CD8+ T-cell expansions in HIV-infected patients on long-term HAART

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1003852107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679229%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

1 reference

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9 February 2020

PubMed publication ID

20679229

1 reference