Protein quality control during erythropoiesis and hemoglobin synthesis (Q34060218)

30 July 2017

title

Protein quality control during erythropoiesis and hemoglobin synthesis (English)

1 reference

30 July 2017

Mitchell J Weiss

2

0 references

author name string

Eugene Khandros

series ordinal

1

1 reference

30 July 2017

publication date

1 December 2010

1 reference

Hematology / Oncology Clinics of North America

30 July 2017

published in

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30 July 2017

volume

24

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30 July 2017

issue

6

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30 July 2017

page(s)

1071-1088

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Methods in mammalian autophagy research

30 July 2017

cites work

1 reference

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Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

5 July 2018

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NIX is required for programmed mitochondrial clearance during reticulocyte maturation

5 July 2018

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Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

5 July 2018

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5 July 2018

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An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis

5 July 2018

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

5 July 2018

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Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1

5 July 2018

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

5 July 2018

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Protein quality control: chaperones culling corrupt conformations

5 July 2018

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Formation of morphologically similar globular aggregates from diverse aggregation-prone proteins in mammalian cells

5 July 2018

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Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma

5 July 2018

1 reference

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Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia

5 July 2018

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Roles of molecular chaperones in protein misfolding diseases

5 July 2018

1 reference

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Protein degradation and protection against misfolded or damaged proteins

5 July 2018

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Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

5 July 2018

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Synthesis of haemoglobin in relation to the maturation of erythroid cells

5 July 2018

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The synthesis of heme and globin in the maturing human erythroid cell

5 July 2018

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Ultrastructural characterization of the erythroid cells in a novel case of congenital anemia

5 July 2018

1 reference

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Parkin accumulation in aggresomes due to proteasome impairment

5 July 2018

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Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

5 July 2018

1 reference

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The effect of proteasome inhibitors on mammalian erythroid terminal differentiation

5 July 2018

1 reference

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An abundant erythroid protein that stabilizes free alpha-haemoglobin

5 July 2018

1 reference

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Hassles with taking out the garbage: aggravating aggresomes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

5 July 2018

1 reference

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Mechanisms underlying ubiquitination

5 July 2018

1 reference

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Impairment of the ubiquitin-proteasome system by protein aggregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

5 July 2018

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

5 July 2018

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Aggresomes, inclusion bodies and protein aggregation

5 July 2018

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Oxidation versus aggregation - how do SOD1 mutants cause ALS?

5 July 2018

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Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

5 July 2018

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Dynamic association of proteasomal machinery with the centrosome

5 July 2018

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Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

5 July 2018

1 reference

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In vivo newly translated polypeptides are sequestered in a protected folding environment

5 July 2018

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Aggresomes: a cellular response to misfolded proteins

5 July 2018

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5 July 2018

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Evidence that the ubiquitin proteolytic pathway is involved in the degradation of precipitated globin chains in thalassaemia

5 July 2018

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A mouse model for beta 0-thalassemia

5 July 2018

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

5 July 2018

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Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells

5 July 2018

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Heat shock-induced translational control of HSP70 and globin synthesis in chicken reticulocytes

5 July 2018

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The fate of excess β-globin chains within erythropoietic cells in α-thalassaemia 2 trait, α-thalassaemia 1 trait, haemoglobin H disease and haemoglobin Q-H disease: an electron microscope study

5 July 2018

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Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown

5 July 2018

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Ultrastructural Studies of Erythropoiesis in β-Thalassaemia Trait

5 July 2018

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Electron Microscope and High Resolution Autoradiographic Studies of the Erythroblasts in Haemoglobin H Disease

5 July 2018

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Autophagic vacuoles in human red cells

5 July 2018

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Hemoglobin synthesis in beta-thalassemia: the properties of the free alpha-chains

5 July 2018

1 reference

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Equal synthesis of - and -globin chains in erythroid precursors in heterozygous -thalassemia

5 July 2018

1 reference

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Studies on the stability of oxyhemoglobin A and its constituent chains and their derivatives.

5 July 2018

1 reference

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The pattern of hemoglobin precipitation in thalassemia and its significance.

5 July 2018

1 reference

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Free alpha-globin pool in human bone marrow

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Autophagy of mitochondria in rat bone marrow erythroid cells. Relation to nuclear extrusion.

5 July 2018

1 reference

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Inclusion body beta-thalassemia trait in a Swiss family is caused by an abnormal hemoglobin (Geneva) with an altered and extended beta chain carboxy-terminus due to a modification in codon beta 114

5 July 2018

1 reference

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Fate of alpha-hemoglobin chains and erythrocyte defects in beta-thalassemia

5 July 2018

1 reference

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Globin synthesis in fractionated Normoblasts of beta-thalassemia heterozygotes

5 July 2018

1 reference

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Imbalanced globin chain synthesis in heterozygous beta-thalassemic bone marrow

5 July 2018

1 reference

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A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Proteolytic activity in erythrocyte precursors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Global changes to the ubiquitin system in Huntington's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Ubiquitylation of nascent globin chains in a cell-free system

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Human reticulocytes isolated from peripheral blood: maturation time and hemoglobin synthesis

28 October 2018

1 reference

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A transgenic mouse model of the ubiquitin/proteasome system

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

28 October 2018

1 reference

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The Mallory body as an aggresome: in vitro studies

28 October 2018

1 reference

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Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Influence of hemoglobin precipitation on erythrocyte metabolism in alpha and beta thalassemia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136498

Proteasome inhibitors in cancer therapy

28 October 2018

1 reference

12 December 2020

Turnover of excess hemoglobin alpha chains in beta-thalassemic cells is ATP-dependent

1 reference

12 December 2020

Autophagy in embryonic erythroid cells: its role in maturation

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12 December 2020

Rapid destruction of newly synthesized excess beta-globin chains in HbH disease

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12 December 2020

Excess of alpha-Globin Synthesis in Homozygous beta-Thalassemia Its Cytoplasmic Molecular Forms

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12 December 2020

Excess of alpha-globin synthesis in homozygous beta-thalassemia and its removal from the red blood cell cytoplasm

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12 December 2020

An analysis of hemoglobin synthesis in erythropoietic cells

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12 December 2020

Precipitation of alpha-chains on the centrioles of erythroblasts in beta-thalassaemia

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12 December 2020

Transfusion-dependent congenital dyserythropoietic anaemia with intraerythroblastic inclusions of a non-globin protein

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12 December 2020

Degradation of Monoubiquitinated .alpha.-Globin by 26S Proteasomes

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12 December 2020

Haemoglobin Synthesis during Erythroid Maturation in β-Thalassaemia

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12 December 2020

Soluble and stroma-bound globin chains in mild and severe beta thalassemia

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12 December 2020

ABSORPTION SPECTRA OF INCLUSION BODIES IN BETA-THALASSEMIA

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12 December 2020

Erythrocytic proteases: preferential degradation of alpha hemoglobin chains

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12 December 2020

Red blood cells contain a pathway for the degradation of oxidant-damaged hemoglobin that does not require ATP or ubiquitin

1 reference

12 December 2020

Intracellular Loss of Free α Chains in β Thalassaemia

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12 December 2020

Properties of abnormal proteins degraded rapidly in reticulocytes. Intracellular aggregation of the globin molecules prior to hydrolysis

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12 December 2020

Mouse beta thalassemia, a model for the membrane defects of erythrocytes in the human disease

1 reference

12 December 2020

Monoubiquitinated alpha globin is an intermediate in the ATP-dependent proteolysis of alpha globin

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12 December 2020

Composition of the intra-erythroblastic precipitates in thalassaemia and congenital dyserythropoietic anaemia (CDA): identification of a new type of CDA with intra-erythroblastic precipitates not reacting with monoclonal antibodies to alpha- and bet

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12 December 2020

Peptide analysis of the inclusions of erythroid cells in β-thalassemia

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12 December 2020

Proteolysis in thalassemia: studies with protease inhibitors

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12 December 2020

Absolute rates of globin chain synthesis in thalassemia

1 reference

12 December 2020

Inclusions of hemoglobin erythroblasts and erythrocytes of thalassemia

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12 December 2020

The ATP-independent pathway in red blood cells that degrades oxidant-damaged hemoglobin

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12 December 2020

ATP-dependent proteolysis of hemoglobin alpha chains in beta-thalassemic hemolysates is ubiquitin-dependent

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12 December 2020

Maturation of the reticulocyte in vitro

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12 December 2020

Observations on the Ultrastructure of Erythropoietic Cells and Reticulum Cells in the Bone Marrow of Patients with Homozygous β-Thalassaemia

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12 December 2020

Kinetic Evidence for the Existence of alpha-Globin Pool in beta-Thalassemic Reticulocytes

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12 December 2020

Ubiquitin aldehyde increases adenosine triphosphate-dependent proteolysis of hemoglobin alpha-subunits in beta-thalassemic hemolysates

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12 December 2020

Evidence for soluble a chains as intermediates in hemoglobin synthesis in the rabbit reticulocyte

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12 December 2020

Abnormal red cell membrane proteolytic activity in severe heterozygous beta-thalassemia

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12 December 2020

Heterogeneity in the structure of the ubiquitin conjugates of human alpha globin

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12 December 2020

Erythroblastic inclusions in dominantly inherited beta thalassemias

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12 December 2020

Ultrastructural Studies in β-Thalassaemia Major

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12 December 2020

Evidence for increased proteolysis in intact beta thalassemia erythroid cells

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12 December 2020

Both proteasomes and lysosomes degrade the activated erythropoietin receptor

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12 December 2020

Ubiquitin-mediated proteolysis centers in HeLa cells: indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome

1 reference

12 December 2020

10.1016/J.HOC.2010.08.013

Identifiers

DOI

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30 July 2017

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30 July 2017

1 reference