The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. (Q34028623)

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6 February 2020

title

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells (English)

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6 February 2020

1 reference

1 reference

9

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7

Maciej Malecki

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6 February 2020

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Krzysztof Wanic

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Andrzej S Krolewski

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author name string

Chong Wee Liew

1

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6 February 2020

Jacek Bochenski

2

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6 February 2020

Dan Kawamori

3

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6 February 2020

Jiang Hu

4

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6 February 2020

Colin A Leech

5

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6 February 2020

James H Warram

8

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Rohit N Kulkarni

11

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6 February 2020

language of work or name

English

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publication date

1 July 2010

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Journal of Clinical Investigation

6 February 2020

published in

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volume

120

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issue

8

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6 February 2020

page(s)

2876-2888

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Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction

6 February 2020

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5 July 2018

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5 July 2018

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Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients

5 July 2018

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The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy

5 July 2018

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Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and dow

5 July 2018

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Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions

5 July 2018

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TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

5 July 2018

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Rab27a: a new face in beta cell metabolism-secretion coupling

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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29 October 2018

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29 October 2018

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The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis

29 October 2018

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29 October 2018

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29 October 2018

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Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice

29 October 2018

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29 October 2018

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Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

29 October 2018

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Fluorescence-activated cell sorted rat islet cells and studies of the insulin secretory process

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20592469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Subcellular distribution and function of Rab3A, B, C, and D isoforms in insulin-secreting cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20592469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20592469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI36849

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20592469%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

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6 February 2020

PubMed publication ID

20592469

1 reference