DNA nicks promote efficient and safe targeted gene correction (Q34017803)

30 July 2017

title

DNA nicks promote efficient and safe targeted gene correction (English)

1 reference

30 July 2017

Luther Davis

1

1 reference

30 July 2017

Nancy Maizels

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 September 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

9

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30 July 2017

page(s)

e23981

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

1 September 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Ex vivo gene transfer and correction for cell-based therapies

28 July 2018

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Gene therapy for primary immunodeficiencies: Looking ahead, toward gene correction

28 July 2018

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More forks on the road to replication stress recovery

28 July 2018

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Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

28 July 2018

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Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification

28 July 2018

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Genome editing with engineered zinc finger nucleases

28 July 2018

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

28 July 2018

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ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

28 July 2018

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Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction

28 July 2018

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Frequent endonuclease cleavage at off-target locations in vivo.

28 July 2018

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Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins

28 July 2018

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Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair

28 July 2018

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28 July 2018

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Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

28 July 2018

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Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

28 July 2018

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Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity

28 July 2018

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Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences

28 July 2018

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DNA damage, homology-directed repair, and DNA methylation

28 July 2018

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Interplay between human DNA repair proteins at a unique double-strand break in vivo

28 July 2018

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

28 July 2018

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Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

28 July 2018

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How homologous recombination is initiated: unexpected evidence for single-strand nicks from v(d)j site-specific recombination

28 July 2018

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A site- and strand-specific DNA break confers asymmetric switching potential in fission yeast

28 July 2018

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28 July 2018

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Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

28 July 2018

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A novel recombinator in yeast based on gene II protein from bacteriophage f1

28 July 2018

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TALEs of genome targeting

28 July 2018

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

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Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

21 January 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

21 January 2018

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RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023981

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023981

Targeting DNA double-strand breaks with TAL effector nucleases

21 January 2018

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Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation

21 January 2018

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10.1371/JOURNAL.PONE.0023981

21 January 2018

Identifiers

DOI

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30 July 2017

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30 July 2017

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