Zinc ions promote Alzheimer Abeta aggregation via population shift of polymorphic states (Q34006345)

30 July 2017

title

Zinc ions promote Alzheimer Abeta aggregation via population shift of polymorphic states (English)

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30 July 2017

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30 July 2017

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Ruth Nussinov

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30 July 2017

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Yifat Miller

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30 July 2017

language of work or name

English

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publication date

6 May 2010

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

107

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30 July 2017

issue

21

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30 July 2017

page(s)

9490-9495

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Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Polymorphism of Alzheimer's Abeta17-42 (p3) oligomers: the importance of the turn location and its conformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Intrinsic disorder in proteins associated with neurodegenerative diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-beta peptide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Effect of dehydration on the aggregation kinetics of two amyloid peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

NMR studies of the Zn2+ interactions with rat and human beta-amyloid (1-28) peptides in water-micelle environment.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Molecular dynamics study of the beta amyloid peptide of Alzheimer's disease and its divalent copper complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid beta-peptide.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Modulating amyloid self-assembly and fibril morphology with Zn(II)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

PatchDock and SymmDock: servers for rigid and symmetric docking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Zinc binding agonist effect on the recognition of the beta-amyloid (4-10) epitope by anti-beta-amyloid antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Anchor residues in protein-protein interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Natural history of Alzheimer's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Folding and binding cascades: dynamic landscapes and population shifts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Folding funnels, binding funnels, and protein function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Rapid induction of Alzheimer A beta amyloid formation by zinc.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Amyloid plaque core protein in Alzheimer disease and Down syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Characterization of the ZnII binding to the peptide amyloid-beta1-16 linked to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Abeta) of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Metal binding in amyloid beta-peptides shows intra- and inter-peptide coordination modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Mechanism of zinc(II)-promoted amyloid formation: zinc(II) binding facilitates the transition from the partially alpha-helical conformer to aggregates of amyloid beta protein(1-28).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Effects of cyclen and cyclam on zinc(II)- and copper(II)-induced amyloid beta-peptide aggregation and neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Mechanism of copper(II) inhibiting Alzheimer's amyloid beta-peptide from aggregation: a molecular dynamics investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Effects of zinc binding on the conformational distribution of the amyloid-beta peptide based on molecular dynamics simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Energy landscape theory for Alzheimer's amyloid beta-peptide fibril elongation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

New analytic approximation to the standard molecular volume definition and its application to generalized Born calculations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Investigations of the molecular mechanism of metal-induced Abeta (1-40) amyloidogenesis

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

29 October 2018

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Modulation of A beta adhesiveness and secretase site cleavage by zinc.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906839

Zinc Binding to Alzheimer's Aβ(1–16) Peptide Results in Stable Soluble Complex

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Zinc binding properties of the amyloid fragment Aβ(1–16) studied by electrospray-ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0913114107

Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease

21 January 2018

1 reference

12 December 2020

Selective destabilization of soluble amyloid β oligomers by divalent metal ions

1 reference

12 December 2020

Amyloid-beta peptide forms monomeric complexes with Cu(II) and Zn(II) prior to aggregation

1 reference

12 December 2020

Examining the zinc binding site of the amyloid-beta peptide

1 reference

12 December 2020

Zinc Lowers Amyloid-β Toxicity by Selectively Precipitating Aggregation Intermediates†

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0913114107

1 reference

release_mfpfxp5usjf4vhmghpuwgnalva

30 July 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mfpfxp5usjf4vhmghpuwgnalva

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2906839

1 reference

30 July 2017

1 reference