Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease (Q33999537)

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English	Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease (English)

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Europe PubMed Central

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30 July 2017

Alzheimer's disease

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Benoit Melchior

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Benoit Melchior

1

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Bor-Kai Hsiung

3

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Harald Neumann

9

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Matthias Staufenbiel

8

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Matthias Staufenbiel

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30 July 2017

author name string

Angie E Garcia

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30 July 2017

Katherine M Lo

4

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Europe PubMed Central

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30 July 2017

Jonathan M Doose

5

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Europe PubMed Central

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30 July 2017

J Cameron Thrash

6

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Europe PubMed Central

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30 July 2017

Anna K Stalder

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Europe PubMed Central

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30 July 2017

Monica J Carson

10

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30 July 2017

publication date

12 July 2010

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Europe PubMed Central

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30 July 2017

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Europe PubMed Central

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30 July 2017

2

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Europe PubMed Central

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30 July 2017

3

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Europe PubMed Central

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30 July 2017

e00037

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Europe PubMed Central

PubMed publication ID

30 July 2017

T cells specifically targeted to amyloid plaques enhance plaque clearance in a mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905103

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Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

1 reference

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P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin

1 reference

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Rett syndrome and other autism spectrum disorders--brain diseases of immune malfunction?

1 reference

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P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide

1 reference

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Microglia: biology and pathology

1 reference

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Expression of complement system components during aging and amyloid deposition in APP transgenic mice

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Signal regulatory protein-beta1: a microglial modulator of phagocytosis in Alzheimer's disease

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Inflammation in transgenic mouse models of neurodegenerative disorders

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Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

1 reference

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5 July 2018

Inflammation, microglia, and Alzheimer's disease

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Restoring immune suppression in the multiple sclerosis brain

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The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor

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Differential gene expression in LPS/IFNgamma activated microglia and macrophages: in vitro versus in vivo

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A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

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Immunotherapy, vascular pathology, and microhemorrhages in transgenic mice

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TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

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Neuronal regulation of immune responses in the central nervous system

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Efficient colonic mucosal wound repair requires Trem2 signaling

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Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

1 reference

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TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

1 reference

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Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease

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Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases.

1 reference

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A rose by any other name? The potential consequences of microglial heterogeneity during CNS health and disease

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TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

1 reference

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Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis

1 reference

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The TREM receptor family and signal integration

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CNS immune privilege: hiding in plain sight

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Microglia and the control of autoreactive T cell responses

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Control of microglial neurotoxicity by the fractalkine receptor

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Amyloid-beta immunotherapy for the prevention and treatment of Alzheimer disease: lessons from mice, monkeys, and humans

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Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

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Neuropsychological tests and functional nuclear neuroimaging provide evidence of subclinical impairment in Nasu-Hakola disease heterozygotes

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The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.

1 reference

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Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

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Role of the immune system in the maintenance of mouse facial motoneuron viability after nerve injury

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CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation

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Nasu-Hakola disease (polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy--PLOSL): a dementia associated with bone cystic lesions. From clinical to genetic and molecular aspects

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Immunotherapeutic Approaches to Alzheimer's Disease

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Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia

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A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905103

5 July 2018

Antibody-mediated phagocytosis of the amyloid beta-peptide in microglia is differentially modulated by C1q.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905103

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Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation

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Mature microglia resemble immature antigen-presenting cells

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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Localization and cell association of C1q in Alzheimer's disease brain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905103

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1 reference

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12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/20640189

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https://pubmed.ncbi.nlm.nih.gov/20640189

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Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1042/AN20100010

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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