Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression (Q33995107)

30 July 2017

title

Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression (English)

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30 July 2017

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9

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30 July 2017

Ivano Condò

4

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author name string

Silvia Cursi

1

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30 July 2017

Alessandra Rufini

2

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30 July 2017

Venturina Stagni

3

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30 July 2017

Vittoria Matafora

5

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30 July 2017

Angela Bachi

6

1 reference

30 July 2017

Antonio Paniccià Bonifazi

7

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30 July 2017

Luigi Coppola

8

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30 July 2017

Roberto Testi

10

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30 July 2017

Daniela Barilà

11

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30 July 2017

language of work or name

English

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publication date

13 April 2006

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30 July 2017

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30 July 2017

volume

25

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30 July 2017

issue

9

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30 July 2017

page(s)

1895-1905

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The interplay between Src family kinases and receptor tyrosine kinases

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis

28 July 2018

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28 July 2018

The flip side of FLIP

1 reference

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Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Src Family Kinases: Potential Targets for the Treatment of Human Cancer and Leukemia

28 July 2018

1 reference

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Interdimer processing mechanism of procaspase-8 activation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Src family kinases in tumor progression and metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

28 July 2018

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Insights into the regulatory mechanism for caspase-8 activation

28 July 2018

1 reference

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A unified model for apical caspase activation

28 July 2018

1 reference

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Src in cancer: deregulation and consequences for cell behaviour

28 July 2018

1 reference

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Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

From bench to clinic with apoptosis-based therapeutic agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Signaling--2000 and beyond

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Regulation of cell death protease caspase-9 by phosphorylation

28 July 2018

1 reference

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Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Caspases: the executioners of apoptosis

28 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601085

Caspase 8 is absent or low in many ex vivo gliomas.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Inactivating mutations of caspase-8 gene in colorectal carcinomas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Caspase-dependent cleavage of c-Abl contributes to apoptosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Death and anti-death: tumour resistance to apoptosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1456929

Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16619028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16619028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7601085

1 reference

30 July 2017

1 reference

30 July 2017

1 reference