Drug-DNA recognition: energetics and implications for design (Q33994672)

30 July 2017

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title

Drug-DNA recognition: energetics and implications for design (English)

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30 July 2017

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Haq I

1

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30 July 2017

Ladbury J

series ordinal

2

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30 July 2017

language of work or name

1 reference

1 July 2000

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Journal of Molecular Recognition

30 July 2017

published in

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30 July 2017

volume

13

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30 July 2017

issue

4

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30 July 2017

page(s)

188-197

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Anthracene-9,10-diones as potential anticancer agents. Synthesis, DNA-binding, and biological studies on a series of 2,6-disubstituted derivatives

30 July 2017

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21 January 2018

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Molecular recognition between a new pentacyclic acridinium salt and DNA sequences investigated by optical spectroscopic techniques, proton nuclear magnetic resonance spectroscopy, and molecular modeling

21 January 2018

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21 January 2018

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Structure-based design of a new bisintercalating anthracycline antibiotic

21 January 2018

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Binding of two distamycin A molecules in the minor groove of an alternating B–DNA duplex

21 January 2018

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Spectroscopic recognition of guanine dimeric hairpin quadruplexes by a carbocyanine dye.

21 January 2018

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Sequence-specific DNA recognition by polyamides

21 January 2018

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Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

21 January 2018

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Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes

21 January 2018

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Rational design of a triple helix-specific intercalating ligand.

21 January 2018

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NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.

21 January 2018

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21 January 2018

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A molecular anchor for stabilizing triple-helical DNA

21 January 2018

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Design of a G.C-specific DNA minor groove-binding peptide.

21 January 2018

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Multistranded DNA structures

21 January 2018

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Regulation of gene expression by small molecules

21 January 2018

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

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Molecular Anchoring of Duplex and Triplex DNA by Disubstituted Anthracene-9,10-diones: Calorimetric, UV Melting, and Competition Dialysis Studies

21 January 2018

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Specific binding of hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: calorimetric and spectroscopic studies

21 January 2018

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Parsing free energies of drug-DNA interactions.

21 January 2018

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Structure of a DNA-bisdaunomycin complex

21 January 2018

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DNA as a target for drug action

21 January 2018

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Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition

21 January 2018

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Targeting multi-stranded DNA structures

21 January 2018

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Thermodynamics and structure of a DNA tetraplex: a spectroscopic and calorimetric study of the tetramolecular complexes of d(TG3T) and d(TG3T2G3T)

21 January 2018

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Crystal structure of four-stranded Oxytricha telomeric DNA

21 January 2018

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A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA

21 January 2018

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Structural basis for G.C recognition in the DNA minor groove

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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Binding of an antitumor drug to DNA, Netropsin and C-G-C-G-A-A-T-T-BrC-G-C-G

21 January 2018

1 reference

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The molecular origin of DNA-drug specificity in netropsin and distamycin

21 January 2018

1 reference

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Counting the calories to stay in the groove.

21 January 2018

1 reference

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The high-resolution crystal structure of a parallel-stranded guanine tetraplex

21 January 2018

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The structure of the DNA-acridine complex

21 January 2018

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Molecular recognition between oligopeptides and nucleic acids: novel imidazole-containing oligopeptides related to netropsin that exhibit altered DNA sequence specificity

21 January 2018

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Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

21 January 2018

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Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin

21 January 2018

1 reference

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22 Molecular modeling to study DNA intercalation by anti-tumor drugs

21 January 2018

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Recent advances in the development of telomerase inhibitors for the treatment of cancer

21 January 2018

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1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase

21 January 2018

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Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination

21 January 2018

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Triple helix formation and the antigene strategy for sequence-specific control of gene expression

21 January 2018

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Binding of Two Novel Bisdaunorubicins to DNA Studied by NMR Spectroscopy,

21 January 2018

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Criteria for the mode of binding of DNA binding agents.

21 January 2018

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Substituent position dictates the intercalative DNA-binding mode for anthracene-9,10-dione antitumor drugs

21 January 2018

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Anthracene-9,10-diones as potential anticancer agents: bacterial mutation studies of amido-substituted derivatives reveal an unexpected lack of mutagenicity

21 January 2018

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On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides

21 January 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

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Monovalent cation-induced structure of telomeric DNA: the G-quartet model

21 January 2018

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Inhibition of telomerase by G-quartet DNA structures

21 January 2018

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10.1002/1099-1352(200007/08)13:4<188::AID-JMR503>3.0.CO;2-1

21 January 2018

Identifiers

DOI

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30 July 2017

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