Establishment of epithelial polarity--GEF who's minding the GAP? (Q33980507)

30 July 2017

title

Establishment of epithelial polarity--GEF who's minding the GAP? (English)

1 reference

30 July 2017

Siu P Ngok

1

1 reference

30 July 2017

Wan-Hsin Lin

series ordinal

2

1 reference

30 July 2017

Panos Z Anastasiadis

series ordinal

3

1 reference

30 July 2017

language of work or name

English

0 references

publication date

2 July 2014

1 reference

30 July 2017

published in

Journal of Cell Science

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30 July 2017

volume

127

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30 July 2017

issue

Pt 15

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30 July 2017

page(s)

3205-3215

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Integrins and epithelial cell polarity

30 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.

5 July 2018

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Drosophila PATJ supports adherens junction stability by modulating Myosin light chain activity

5 July 2018

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β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity

5 July 2018

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The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.

5 July 2018

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Rap2A links intestinal cell polarity to brush border formation

5 July 2018

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Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis

5 July 2018

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Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

5 July 2018

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Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling

5 July 2018

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Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium

5 July 2018

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Scrib regulates HGF-mediated epithelial morphogenesis and is stabilized by Sgt1-HSP90.

5 July 2018

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aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation

5 July 2018

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The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro

5 July 2018

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Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF

5 July 2018

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Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases

5 July 2018

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5 July 2018

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Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation

5 July 2018

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A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

5 July 2018

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5 July 2018

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Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

5 July 2018

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A novel role for 14-3-3sigma in regulating epithelial cell polarity

5 July 2018

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aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

5 July 2018

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Bazooka is required for polarisation of the Drosophila anterior-posterior axis

5 July 2018

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Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded

5 July 2018

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5 July 2018

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5 July 2018

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Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions

5 July 2018

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The neuronal RhoA GEF, Tech, interacts with the synaptic multi-PDZ-domain-containing protein, MUPP1.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization

5 July 2018

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Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions

5 July 2018

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aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia

5 July 2018

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The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation

5 July 2018

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PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

5 July 2018

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aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

5 July 2018

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PALS1 regulates E-cadherin trafficking in mammalian epithelial cells

5 July 2018

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p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.

5 July 2018

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Catching a GEF by its tail

5 July 2018

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Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration

5 July 2018

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The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

5 July 2018

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Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells.

5 July 2018

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FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling

5 July 2018

1 reference

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Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains

5 July 2018

1 reference

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PAR1b promotes cell-cell adhesion and inhibits dishevelled-mediated transformation of Madin-Darby canine kidney cells

5 July 2018

1 reference

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Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6.

5 July 2018

1 reference

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A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells

5 July 2018

1 reference

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Tiam1 takes PARt in cell polarity

5 July 2018

1 reference

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Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity.

5 July 2018

1 reference

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Lethal giant larvae take on a life of their own.

5 July 2018

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A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype

5 July 2018

1 reference

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Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of gamma-secretase activity

5 July 2018

1 reference

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The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

5 July 2018

1 reference

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CZH proteins: a new family of Rho-GEFs

5 July 2018

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The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

5 July 2018

1 reference

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Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells

5 July 2018

1 reference

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PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells

5 July 2018

1 reference

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Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells

5 July 2018

1 reference

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hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells

5 July 2018

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Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Characterization of the Crumbs homolog 2 (CRB2) gene and analysis of its role in retinitis pigmentosa and Leber congenital amaurosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

PATJ regulates tight junction formation and polarity in mammalian epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The GDP-bound form of Arf6 is located at the plasma membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Parsing the polarity code

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Loss of PALS1 expression leads to tight junction and polarity defects.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

EFA6, exchange factor for ARF6, regulates the actin cytoskeleton and associated tight junction in response to E-cadherin engagement.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Involvement of Nectin-activated Cdc42 Small G Protein in Organization of Adherens and Tight Junctions in Madin-Darby Canine Kidney Cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Regulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Cell polarity: the ups and downs of the Par6/aPKC complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Redox-dependent downregulation of Rho by Rac.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Rho GTPase-activating proteins in cell regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Rho GTPases in cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Composition and formation of intercellular junctions in epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Trans-interactions of nectins induce formation of filopodia and Lamellipodia through the respective activation of Cdc42 and Rac small G proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Assembly of epithelial tight junctions is negatively regulated by Par6.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

PARsing embryonic polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

GIT proteins, A novel family of phosphatidylinositol 3,4, 5-trisphosphate-stimulated GTPase-activating proteins for ARF6

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

The Drosophila genes crumbs and stardust are involved in the biogenesis of adherens junctions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Regulation and function of the Rho subfamily of small GTPases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

CRUMBS is involved in the control of apical protein targeting during Drosophila epithelial development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

GAPs for rho-related GTPases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Malignant Neoplasms of Genetic Origin in Drosophila melanogaster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Mutation in MPDZ causes severe congenital hydrocephalus.

5 July 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Integrated activity of PDZ protein complexes regulates epithelial polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

NG2 regulates directional migration of oligodendrocyte precursor cells via Rho GTPases and polarity complex proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Cdc42, Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens junction stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Interaction of Par-6 and Crumbs complexes is essential for photoreceptor morphogenesis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Domain-specific early and late function of Dpatj in Drosophila photoreceptor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Tissue-specific function of Patj in regulating the Crumbs complex and epithelial polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Mpdz is a quantitative trait gene for drug withdrawal seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Crumbs/DaPKC-dependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

PAR-1 kinase phosphorylates Dlg and regulates its postsynaptic targeting at the Drosophila neuromuscular junction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117226

Nucleotide exchange factor ECT2 regulates epithelial cell polarity

29 October 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

Self-association of PAR-3-mediated by the Conserved N-terminal Domain Contributes to the Development of Epithelial Tight Junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.153197

E-cadherin-mediated cell-cell attachment activates Cdc42

21 January 2018

1 reference

12 December 2020

Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium

1 reference

12 December 2020

Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions

1 reference

12 December 2020

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : II. Zygotic loci on the third chromosome

1 reference

12 December 2020

Identification of genes required for cytoplasmic localization in early C. elegans embryos

1 reference

12 December 2020

Cytomechanics of cadherin-mediated cell-cell adhesion

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.153197

1 reference

release_2nrdrvr2trbodmozsyeh7j3kc4

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2nrdrvr2trbodmozsyeh7j3kc4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4117226

1 reference

30 July 2017

1 reference