Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis (Q33962607)

30 July 2017

title

Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis (English)

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19

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Phioanh Nghiemphu

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Annabel Parret

13

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Ludwine Messiaen

20

object named as

Ludwine Messiaen

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Rameen Beroukhim

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author name string

Lauren T McGillicuddy

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Jody A Fromm

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Pablo E Hollstein

3

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Sara Kubek

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Thomas De Raedt

6

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Bryan W Johnson

7

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Sybil M G Williams

8

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Linda M Liau

10

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Tim F Cloughesy

11

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Paul S Mischel

12

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Jeanette Seiler

14

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Gerd Moldenhauer

15

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Klaus Scheffzek

16

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Anat O Stemmer-Rachamimov

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Charles L Sawyers

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Ingo K Mellinghoff

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Karen Cichowski

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publication date

1 July 2009

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30 July 2017

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30 July 2017

volume

16

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issue

1

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30 July 2017

page(s)

44-54

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

30 July 2017

cites work

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Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

5 July 2018

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5 July 2018

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5 July 2018

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Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

5 July 2018

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5 July 2018

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5 July 2018

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Down-regulation of the inhibitor of growth 1 (ING1) tumor suppressor sensitizes p53-deficient glioblastoma cells to cisplatin-induced cell death

5 July 2018

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Ubiquitination regulates PTEN nuclear import and tumor suppression

5 July 2018

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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

5 July 2018

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

5 July 2018

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Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

5 July 2018

1 reference

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

5 July 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

5 July 2018

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Tumour biology: senescence in premalignant tumours

5 July 2018

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The NF1 tumor suppressor critically regulates TSC2 and mTOR.

5 July 2018

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Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells

5 July 2018

1 reference

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Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor

5 July 2018

1 reference

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Targeting RAS signalling pathways in cancer therapy

5 July 2018

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Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?

5 July 2018

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

5 July 2018

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Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide

5 July 2018

1 reference

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Molecular analysis at the NF1 locus in astrocytic brain tumors.

5 July 2018

1 reference

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Analysis of the p53 gene and its expression in human glioblastoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

5 July 2018

1 reference

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 July 2018

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Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

5 July 2018

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5 July 2018

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The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

5 July 2018

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A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

5 July 2018

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

5 July 2018

1 reference

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Somatic mutations in the neurofibromatosis 1 gene in human tumors

5 July 2018

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

5 July 2018

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Targeting the protein kinase C family: are we there yet?

5 July 2018

1 reference

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A negative feedback signaling network underlies oncogene-induced senescence

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Exhaustive mutation analysis of the NF1 gene allows identification of 95% of mutations and reveals a high frequency of unusual splicing defects

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Somatic mutations in the neurofibromatosis 1 gene in gliomas and primitive neuroectodermal tumours.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Neurofibromatosis type 1 gene mutations in neuroblastoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

29 October 2018

Senescence comes of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Stimulation of p21 ras upon T-cell activation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897249

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

29 October 2018

1 reference

12 December 2020

The sevenfold way of PKC regulation

1 reference

12 December 2020

Spectrum of single- and multiexon NF1 copy number changes in a cohort of 1,100 unselected NF1 patients

1 reference

12 December 2020

Mutations in the neurofibromatosis 1 gene in sporadic malignant melanoma cell lines

1 reference

12 December 2020

Nature and mRNA effect of 282 different NF1 point mutations: focus on splicing alterations

1 reference

12 December 2020

10.1016/J.CCR.2009.05.009

Identifiers

DOI

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30 July 2017

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30 July 2017

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