Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial (Q33946929)

30 July 2017

title

Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial (English)

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30 July 2017

main subject

phase II clinical trial

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cabozantinib

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ChEBI release 2020-05-28

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18

Patrick Schöffski

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30 July 2017

8

Eric J Small

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30 July 2017

Nicholas J. Vogelzang

7

object named as

Nicholas J Vogelzang

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Christopher Logothetis

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object named as

Christopher Logothetis

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David C Smith

1

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Matthew R Smith

2

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30 July 2017

Christopher Sweeney

3

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Aymen A Elfiky

4

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Paul G Corn

6

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Andrea L Harzstark

9

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Michael S Gordon

10

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Ulka N Vaishampayan

11

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Naomi B Haas

12

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Alexander I Spira

13

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Primo N Lara

14

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Chia-Chi Lin

15

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Sandy Srinivas

16

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Avishay Sella

17

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Christian Scheffold

19

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Aaron L Weitzman

20

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Maha Hussain

21

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language of work or name

English

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publication date

19 November 2012

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Journal of Clinical Oncology

30 July 2017

published in

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30 July 2017

volume

31

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30 July 2017

issue

4

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30 July 2017

page(s)

412-419

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Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401.

30 July 2017

cites work

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5 July 2018

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Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth

5 July 2018

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VEGF and c-Met Blockade Amplify Angiogenesis Inhibition in Pancreatic Islet Cancer

5 July 2018

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Activity of XL184 (Cabozantinib), an Oral Tyrosine Kinase Inhibitor, in Patients With Medullary Thyroid Cancer

5 July 2018

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Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer

5 July 2018

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Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate

5 July 2018

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Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells

5 July 2018

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Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer

5 July 2018

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Vascular endothelial growth factor regulates osteoblast survival - evidence for an autocrine feedback mechanism

5 July 2018

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The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression

5 July 2018

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Involvement of hepatocyte growth factor in the development of bone metastasis of a mouse mammary cancer cell line, BALB/c-MC.

5 July 2018

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Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair

5 July 2018

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High expression of the Met receptor in prostate cancer metastasis to bone

5 July 2018

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

5 July 2018

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Hepatocyte growth factor is a coupling factor for osteoclasts and osteoblasts in vitro.

5 July 2018

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Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinoma

5 July 2018

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c-met proto-oncogene expression in benign and malignant human prostate tissues

5 July 2018

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A phase II clinical trial of sorafenib in androgen-independent prostate cancer

5 July 2018

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Microarray analysis of prostate cancer progression to reduced androgen dependence: studies in unique models contrasts early and late molecular events

29 October 2018

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Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480.

29 October 2018

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Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study

29 October 2018

1 reference

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Regulation of release of hepatocyte growth factor from human promyelocytic leukemia cells, HL-60, by 1,25-dihydroxyvitamin D3, 12-O-tetradecanoylphorbol 13-acetate, and dibutyryl cyclic adenosine monophosphate.

29 October 2018

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Prognostic Significance of Plasma Scatter Factor/Hepatocyte Growth Factor Levels in Patients with Metastatic Hormone- Refractory Prostate Cancer: Results from Cancer and Leukemia Group B 150005/9480

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23169517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23169517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23169517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1200/JCO.2012.45.0494

1 reference

30 July 2017

1 reference

30 July 2017

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