From Alzheimer's disease to skin tumors: the catenin connection (Q33943557)

30 July 2017

title

From Alzheimer's disease to skin tumors: the catenin connection (English)

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30 July 2017

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Hartmann D

1

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30 July 2017

language of work or name

English

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publication date

1 September 2001

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

number of pages

2

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based on heuristic

inferred from page(s)

published in

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30 July 2017

volume

98

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30 July 2017

issue

19

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30 July 2017

page(s)

10522-10523

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Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis

30 July 2017

cites work

1 reference

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

5 July 2018

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Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

5 July 2018

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beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

5 July 2018

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Where Notch and Wnt signaling meet. The presenilin hub

5 July 2018

1 reference

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Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

5 July 2018

1 reference

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Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Beauty is skin deep: the fascinating biology of the epidermis and its appendages

5 July 2018

1 reference

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Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

5 July 2018

1 reference

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The role of beta-catenin stability in mutant PS1-associated apoptosis

5 July 2018

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Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway

5 July 2018

1 reference

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Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

5 July 2018

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Presenilin is required for activity and nuclear access of Notch in Drosophila

5 July 2018

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

5 July 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

5 July 2018

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The Notch signalling pathway in hair growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Direct association of presenilin-1 with beta-catenin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Lack of beta-catenin affects mouse development at gastrulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.211430698

Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.211430698

Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58494

29 October 2018

Identifiers

DOI

10.1073/PNAS.211430698

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30 July 2017

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30 July 2017

1 reference