Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin. (Q33936687)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15809436%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin (English)

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10 January 2020

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1

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10 January 2020

author name string

Gad Asher

2

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10 January 2020

Veronica Reiss

3

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10 January 2020

Yosef Shaul

4

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10 January 2020

Leo Sachs

5

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10 January 2020

Joseph Lotem

6

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10 January 2020

language of work or name

English

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publication date

4 April 2005

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Proceedings of the National Academy of Sciences of the United States of America

10 January 2020

published in

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10 January 2020

volume

102

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10 January 2020

issue

15

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10 January 2020

page(s)

5535-5540

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A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

10 January 2020

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NAD+ modulates p53 DNA binding specificity and function

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Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma.

5 July 2018

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The ubiquitin ligase COP1 is a critical negative regulator of p53

5 July 2018

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Curcumin impairs tumor suppressor p53 function in colon cancer cells

5 July 2018

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5 July 2018

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P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1

5 July 2018

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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

5 July 2018

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Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

5 July 2018

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Identification of ErbB-2 kinase domain motifs required for geldanamycin-induced degradation

5 July 2018

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Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.

5 July 2018

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Cytokine control of developmental programs in normal hematopoiesis and leukemia

5 July 2018

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NQO1 stabilizes p53 through a distinct pathway

5 July 2018

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Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction

5 July 2018

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Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches

5 July 2018

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COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

5 July 2018

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Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1

5 July 2018

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5 July 2018

Surfing the p53 network

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The p53 tumor suppressor gene: from molecular biology to clinical investigation.

5 July 2018

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5 July 2018

Thioredoxin reductase

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Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu

5 July 2018

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5 July 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

5 July 2018

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Disruption of the DT Diaphorase (NQO1) Gene in Mice Leads to Increased Menadione Toxicity

5 July 2018

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The Physical Association of Multiple Molecular Chaperone Proteins with Mutant p53 Is Altered by Geldanamycin, an hsp90-Binding Agent

5 July 2018

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Regulation of p53 stability by Mdm2

5 July 2018

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Mdm2 promotes the rapid degradation of p53

5 July 2018

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p53, the cellular gatekeeper for growth and division

5 July 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

5 July 2018

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Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

5 July 2018

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Database of p53 gene somatic mutations in human tumors and cell lines

5 July 2018

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Comparative study of the binding of coumarin anticoagulants and serum albumins.

5 July 2018

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Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

5 July 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

5 July 2018

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p53 function and dysfunction

5 July 2018

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p53: the ultimate tumor suppressor gene?

5 July 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

5 July 2018

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Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501828102

Photophysical studies on binding of curcumin to bovine serum albumins

21 January 2018

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Inhibition of nuclear factor kappaB by direct modification in whole cells--mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers

21 January 2018

1 reference

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Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501828102

Green tea polyphenol and curcumin inversely regulate human involucrin promoter activity via opposing effects on CCAAT/enhancer-binding protein function

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0501828102

Cytokines as suppressors of apoptosis

21 January 2018

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12 December 2020

DT-diaphorase: purification, properties, and function

1 reference

12 December 2020

Interaction of curcumin with human serum albumin--a spectroscopic study

1 reference

12 December 2020

Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0501828102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15809436%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15809436%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

15809436

1 reference