The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded (Q33934781)

30 July 2017

title

The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded (English)

1 reference

30 July 2017

main subject

transmembrane protein

0 references

Merlin Dmel_CG14228

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Expanded Dmel_CG4114

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Crumbs Dmel_CG6383

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Kibra Dmel_CG33967

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author name string

Chen Ling

1

1 reference

30 July 2017

Yonggang Zheng

2

1 reference

30 July 2017

Feng Yin

3

1 reference

30 July 2017

Jianzhong Yu

4

1 reference

30 July 2017

Juan Huang

5

1 reference

30 July 2017

Yang Hong

6

1 reference

30 July 2017

Shian Wu

7

1 reference

30 July 2017

Duojia Pan

8

1 reference

30 July 2017

language of work or name

English

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publication date

24 May 2010

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

107

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30 July 2017

issue

23

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30 July 2017

page(s)

10532-10537

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Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

The WW domain protein Kibra acts upstream of Hippo in Drosophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Kibra is a regulator of the Salvador/Warts/Hippo signaling network

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Herding Hippos: regulating growth in flies and man.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

The Hippo pathway regulates apical-domain size independently of its growth-control function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

From the Cover: Directed, efficient, and versatile modifications of the Drosophila genome by genomic engineering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Morphogen control of wing growth through the Fat signaling pathway.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Fat and expanded act in parallel to regulate growth through warts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Hippo signaling in organ size control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Delineation of a Fat tumor suppressor pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Endocytic control of epithelial polarity and proliferation in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

Integrated activity of PDZ protein complexes regulates epithelial polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004279107

The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890787

29 October 2018

Identifiers

DOI

10.1073/PNAS.1004279107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference