Mitotic chromosomal instability and cancer: mouse modelling of the human disease. (Q33926467)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Mitotic chromosomal instability and cancer: mouse modelling of the human disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Juan Manuel Schvartzman

1 reference

ORCID Public Data File 2021

author name string

Juan-Manuel Schvartzman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Robert Benezra

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

1 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

10

1 reference

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17 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

102-115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

17 January 2020

cites work

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Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

5 July 2018

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On the karyotypic origin and evolution of cancer cells

5 July 2018

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Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

5 July 2018

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

5 July 2018

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Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice

5 July 2018

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A mechanism linking extra centrosomes to chromosomal instability

5 July 2018

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Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer

5 July 2018

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MAD2 as a key component of mitotic checkpoint: A probable prognostic factor for gastric cancer

5 July 2018

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Chromosomal instability determines taxane response

5 July 2018

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Aurora-A expression is independently associated with chromosomal instability in colorectal cancer

5 July 2018

1 reference

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BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis

5 July 2018

1 reference

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PTTG overexpression promotes lymph node metastasis in human esophageal squamous cell carcinoma

5 July 2018

1 reference

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Deregulated Aurora-B induced tetraploidy promotes tumorigenesis

5 July 2018

1 reference

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High cyclin B1 expression is associated with poor survival in breast cancer

5 July 2018

1 reference

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Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex

5 July 2018

1 reference

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Identification of Polo-like kinase 1 as a potential therapeutic target in anaplastic thyroid carcinoma

5 July 2018

1 reference

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BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase

5 July 2018

1 reference

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Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis

5 July 2018

1 reference

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Aurora-A kinase is essential for bipolar spindle formation and early development

5 July 2018

1 reference

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Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice

5 July 2018

1 reference

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Reflecting on 25 years with MYC.

5 July 2018

1 reference

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The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

5 July 2018

1 reference

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Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo

5 July 2018

1 reference

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Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding

5 July 2018

1 reference

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Aurora A is essential for early embryonic development and tumor suppression

5 July 2018

1 reference

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Polo-like kinase 1 is essential for early embryonic development and tumor suppression

5 July 2018

1 reference

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Whole chromosome instability and cancer: a complex relationship

5 July 2018

1 reference

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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

5 July 2018

1 reference

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The Aurora kinase family in cell division and cancer.

5 July 2018

1 reference

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Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

5 July 2018

1 reference

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Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis

5 July 2018

1 reference

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Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha

5 July 2018

1 reference

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The pituitary tumor transforming gene 1 (PTTG-1): an immunological target for multiple myeloma

5 July 2018

1 reference

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Examining the link between chromosomal instability and aneuploidy in human cells

5 July 2018

1 reference

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Aneuploidy: instigator and inhibitor of tumorigenesis

5 July 2018

1 reference

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Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

5 July 2018

1 reference

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The genetics of hereditary colon cancer

5 July 2018

1 reference

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Bub1 maintains centromeric cohesion by activation of the spindle checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Replication and protection of telomeres

5 July 2018

1 reference

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Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.

5 July 2018

1 reference

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Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation

5 July 2018

1 reference

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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

5 July 2018

1 reference

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The spindle-assembly checkpoint in space and time

5 July 2018

1 reference

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Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint

5 July 2018

1 reference

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Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles

5 July 2018

1 reference

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A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy

5 July 2018

1 reference

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Targeted anti-mitotic therapies: can we improve on tubulin agents?

5 July 2018

1 reference

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Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

5 July 2018

1 reference

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Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis

5 July 2018

1 reference

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Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer

5 July 2018

1 reference

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RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts.

5 July 2018

1 reference

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Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint

5 July 2018

1 reference

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Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer

5 July 2018

1 reference

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Significance of pituitary tumor transforming gene 1 (PTTG1) in prostate cancer

5 July 2018

1 reference

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Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer

5 July 2018

1 reference

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Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

BubR1 is involved in regulation of DNA damage responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Centrosome amplification induced by hydroxyurea leads to aneuploidy in pRB deficient human and mouse fibroblasts.

5 July 2018

1 reference

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Proteomic identification of differentially-expressed genes in human gastric carcinomas

5 July 2018

1 reference

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5 July 2018

1 reference

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Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice

5 July 2018

1 reference

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How do so few control so many?

5 July 2018

1 reference

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Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Spindle multipolarity is prevented by centrosomal clustering.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Association of MAD2 expression with mitotic checkpoint competence in hepatoma cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Transcriptional abnormality of the hsMAD2 mitotic checkpoint gene is a potential link to hepatocellular carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Timing and checkpoints in the regulation of mitotic progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

High expression of Aurora-B/Aurora and Ipll-like midbody-associated protein (AIM-1) in astrocytomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

ONCOMINE: a cancer microarray database and integrated data-mining platform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Microtubules as a target for anticancer drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Molecular targets for tumour progression in gastrointestinal stromal tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The Aurora kinases: role in cell transformation and tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Alterations in cell cycle genes in early stage lung adenocarcinoma identified by expression profiling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766T.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mad2 phosphorylation regulates its association with Mad1 and the APC/C.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

A molecular signature of metastasis in primary solid tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Gene expression patterns in human liver cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Expression of hBUB1 in acute myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Diversity of gene expression in adenocarcinoma of the lung

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Comparative expression of the mitotic regulators SAK and PLK in colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aneuploid colon cancer cells have a robust spindle checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Molecular analyses of the mitotic checkpoint components hsMAD2, hBUB1 and hBUB3 in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Expression and mutational analyses of the human MAD2L1 gene in breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Somatic mutation of the hBUB1 mitotic checkpoint gene in primary lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Prognostic significance of polo-like kinase expression in esophageal carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mad2 transiently associates with an APC/p55Cdc complex during mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mutations of mitotic checkpoint genes in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Genetic instability in colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Identification of a human mitotic checkpoint gene: hsMAD2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Cellular Oncogenes and Multistep Carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Human-tumor-derived cell lines contain common and different transforming genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Feedback control of mitosis in budding yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Effects of an Rb mutation in the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.

5 July 2018

1 reference

Expression of Aurora kinase A and B in normal and malignant cervical tissue: high Aurora A kinase expression in squamous cervical cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The cohesin ring concatenates sister DNA molecules

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Genomic stability and tumour suppression by the APC/C cofactor Cdh1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mitotic checkpoint gene MAD1 in hepatocellular carcinoma is associated with tumor recurrence after surgical resection.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aurora B kinase expression in ependymal neoplasms.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aneuploidy acts both oncogenically and as a tumor suppressor

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Pituitary tumor transforming gene overexpression facilitates pituitary tumor development.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patients.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of pituitary tumor transforming gene 1 in HCC is associated with angiogenesis and poor prognosis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Alteration of subcellular and cellular expression patterns of cyclin B1 in renal cell carcinoma is significantly related to clinical progression and survival of patients.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Cancer in xeroderma pigmentosum and related disorders of DNA repair

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Aurora B expression in normal testis and seminomas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Improved grading of breast adenocarcinomas based on genomic instability

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

RAS oncogenes: the first 30 years.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Mutations in the mitotic check point gene, MAD1L1, in human cancers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

The spindle assembly checkpoint

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Expression profiling of primary non-small cell lung cancer for target identification

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5526619

Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency

29 October 2018

1 reference

Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice

31 March 2020

1 reference

Amplification/overexpression of a mitotic kinase gene in human bladder cancer

31 March 2020

1 reference

Observation of Y(2175) in J/psi --> etaphif0 (980)

31 March 2020

1 reference

Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy

31 March 2020

1 reference

A diagnostic marker set for invasion, proliferation, and aggressiveness of prolactin pituitary tumors

31 March 2020

1 reference

Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array

31 March 2020

1 reference

Prognostic value of cyclin B1 in patients with esophageal squamous cell carcinoma

31 March 2020

1 reference

The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer

31 March 2020

1 reference

Search for in vivo somatic mutations in the mitotic checkpoint gene, hMAD1, in human lung cancers

31 March 2020

1 reference

Clinical implication of altered expression of Mad1 protein in human breast carcinoma

31 March 2020

1 reference

Aberrant MAD2 expression in soft-tissue sarcoma

31 March 2020

1 reference

Molecular cloning of pituitary tumor transforming gene 1 from ovarian tumors and its expression in tumors

31 March 2020

1 reference

Expression of pituitary-tumour transforming gene in colorectal tumours

31 March 2020

1 reference

Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines

31 March 2020

1 reference

Overexpression of the mitotic spindle assembly checkpoint genes hBUB1, hBUBR1 and hMAD2 in thyroid carcinomas with aggressive nature

31 March 2020

1 reference

12 December 2020

Overexpression of pituitary tumor-transforming gene-1 in hepatocellular carcinoma

1 reference

12 December 2020

Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability

1 reference

12 December 2020

A role for the pituitary tumor-transforming gene in the genesis and progression of non-small cell lung carcinomas

1 reference

12 December 2020

Control of G2 delay by the rad9 gene of Saccharomyces cerevisiae

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2781

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 January 2020

1041793251

0 references

Fatcat ID

release_sded4escnjdyhbwgekkj2swqna

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sded4escnjdyhbwgekkj2swqna

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094045%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

20094045

1 reference