G-protein mediated gating of inward-rectifier K+ channels (Q33918594)

30 July 2017

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title

G-protein mediated gating of inward-rectifier K+ channels (English)

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30 July 2017

M D Mark

1

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30 July 2017

S Herlitze

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

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30 July 2017

volume

267

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30 July 2017

issue

19

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30 July 2017

page(s)

5830-5836

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G proteins: transducers of receptor-generated signals

30 July 2017

cites work

1 reference

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Heterotrimeric G proteins: organizers of transmembrane signals

21 January 2018

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Signalling Via the G Protein-Activated K+ Channels

21 January 2018

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G protein-coupled mechanisms and nervous signaling

21 January 2018

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Atrial G protein-activated K+ channel: expression cloning and molecular properties

21 January 2018

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Primary structure and functional expression of a mouse inward rectifier potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins

21 January 2018

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Vagal and sympathetic effects on the pacemaker fibers in the sinus venosus of the heart

21 January 2018

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On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins

21 January 2018

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Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogue

21 January 2018

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GTP-binding proteins couple cardiac muscarinic receptors to a K channel.

21 January 2018

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Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

21 January 2018

1 reference

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The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.

21 January 2018

1 reference

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Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel

21 January 2018

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Activation of atrial muscarinic K+ channels by low concentrations of beta gamma subunits of rat brain G protein

21 January 2018

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On the mechanism of G protein beta gamma subunit activation of the muscarinic K+ channel in guinea pig atrial cell membrane. Comparison with the ATP-sensitive K+ channel

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits

21 January 2018

1 reference

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A region of the muscarinic-gated atrial K+ channel critical for activation by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Muscarinic K+ channels are activated by beta gamma subunits and inhibited by the GDP-bound form of alpha subunit of transducin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

G beta gamma directly binds to the carboxyl terminus of the G protein-gated muscarinic K+ channel, GIRK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Identification of domains conferring G protein regulation on inward rectifier potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Identification of structural elements involved in G protein gating of the GIRK1 potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins

21 January 2018

1 reference

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Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity

21 January 2018

1 reference

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Structural determinants for interaction with three different effectors on the G protein beta subunit.

21 January 2018

1 reference

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Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Opposing mechanisms of regulation of a G-protein-coupled inward rectifier K+ channel in rat brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit

21 January 2018

1 reference

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Time resolved kinetics of direct G beta 1 gamma 2 interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Identification of a potassium channel site that interacts with G protein betagamma subunits to mediate agonist-induced signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

RGS8 accelerates G-protein-mediated modulation of K+currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Regulators of G protein signaling (RGS) proteins constitutively activate Gbeta gamma-gated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

New roles for RGS2, 5 and 8 on the ratio-dependent modulation of recombinant GIRK channels expressed in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Regulation of GIRK channel deactivation by Galpha(q) and Galpha(i/o) pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Activation of the atrial K ACh channel by the βγ subunits of G proteins or intracellular Na + ions depends on the presence of phosphatidylinositol phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Synergistic activation of G protein-gated inwardly rectifying potassium channels by the betagamma subunits of G proteins and Na(+) and Mg(2+) ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Gating of G protein-sensitive inwardly rectifying K+ channels through phosphatidylinositol 4,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Molecular determinants for sodium-dependent activation of G protein-gated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Inhibition of the hyperpolarization-activated current (if) induced by acetylcholine in rabbit sino-atrial node myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Targeted inactivation of αi2or αi3disrupts activation of the cardiac muscarinic K+channel, IK+Ach, in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Abnormal heart rate regulation in GIRK4 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Identification of the weaver mouse mutation: the end of the beginning

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Nonselective and G betagamma-insensitive weaver K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Evidence of elevated intracellular calcium levels in weaver homozygote mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Production of Membrane Potential Changes in the Frog's Heart by Inhibitory Nerve Impulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01670.X

10.1046/J.1432-1327.2000.01670.X

21 January 2018

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DOI

1 reference

30 July 2017

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