Merotelic attachments and non-homologous end joining are the basis of chromosomal instability. (Q33884341)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20478024%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

editorial

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title

Merotelic attachments and non-homologous end joining are the basis of chromosomal instability (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20478024%20AND%20SRC:MED&resulttype=core&format=json

Karel Hermanus Martinus van Wely

2 February 2020

author

series ordinal

3

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2 February 2020

author name string

Astrid Alonso Guerrero

series ordinal

1

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2 February 2020

Carlos Martínez-A

series ordinal

2

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2 February 2020

publication date

17 May 2010

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2 February 2020

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2 February 2020

volume

5

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2 February 2020

page(s)

13

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Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal

2 February 2020

cites work

1 reference

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The landscape of somatic copy-number alteration across human cancers

5 July 2018

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Signatures of mutation and selection in the cancer genome

5 July 2018

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Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle.

5 July 2018

1 reference

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DNA damage checkpoints: from initiation to recovery or adaptation

5 July 2018

1 reference

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Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability

5 July 2018

1 reference

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The Stability of Broken Ends of Chromosomes in Zea Mays.

5 July 2018

1 reference

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Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors.

5 July 2018

1 reference

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A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH.

5 July 2018

1 reference

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BubR1 is involved in regulation of DNA damage responses

5 July 2018

1 reference

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The life and death of DNA-PK.

5 July 2018

1 reference

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Effect of Ku86 and DNA-PKcs deficiency on non-homologous end-joining and homologous recombination using a transient transfection assay.

5 July 2018

1 reference

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Kinetochore-microtubule interactions during cell division.

5 July 2018

1 reference

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Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer.

5 July 2018

1 reference

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Chromosome segregation and genomic stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Mechanisms of DNA double strand break repair and chromosome aberration formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

5 July 2018

1 reference

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Correcting improper chromosome-spindle attachments during cell division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Chromosomes in a marsupial (Potorous tridactylis) tissue culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Merotelic kinetochore orientation occurs frequently during early mitosis in mammalian tissue cells and error correction is achieved by two different mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Pathways of DNA double-strand break repair during the mammalian cell cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Efficient rejoining of radiation-induced DNA double-strand breaks in centromeric DNA of human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Chromosome nondisjunction and loss induced by protons and X rays in primary human fibroblasts: role of centromeres in aneuploidy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Reduced joining of DNA double strand breaks with an abnormal mutation spectrum in rodent mutants of DNA-PKcs and Ku80.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Aneuploidy in male Indian muntjac cells is limited to the Y2 chromosome

5 July 2018

1 reference

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Mitotic repression of the transcriptional machinery.

5 July 2018

1 reference

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Comparative chromosome painting between two marsupials: origins of an XX/XY1Y2 sex chromosome system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Atm-deficient mice: a paradigm of ataxia telangiectasia

5 July 2018

1 reference

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Mitotic non-disjunction as a mechanism for in vitro aneuploidy induction by X-rays in primary human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Indian Muntjac, Muntiacus muntjak : A Deer with a Low Diploid Chromosome Number

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Antikinetochore antibodies interfere with prometaphase but not anaphase chromosome movement in living PtK2 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Surface functions during Mitosis I: phagocytosis, pinocytosis and mobility of surface-bound Con A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Are aneuploidy and chromosome breakage caused by a CINgle mechanism?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Qualitative and quantitative analysis of phosphorylated ATM foci induced by low-dose ionizing radiation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

29 October 2018

Aneuploidy and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Merotelic kinetochore orientation versus chromosome mono-orientation in the origin of lagging chromosomes in human primary cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

Detection of chromosomal breakage in the 1cen-1q12 region of interphase human lymphocytes using multicolor fluorescence in situ hybridization with tandem DNA probes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878296

DNA-PK-independent rejoining of DNA double-strand breaks in human cell extracts in vitro

29 October 2018

1 reference

12 December 2020

Myeloid leukemias have increased activity of the nonhomologous end-joining pathway and concomitant DNA misrepair that is dependent on the Ku70/86 heterodimer

1 reference

12 December 2020

Anaphase Spindle Mechanics Prevent Mis-Segregation of Merotelically Oriented Chromosomes

1 reference

12 December 2020

Tumor specific modulation of KU70/80 DNA binding activity in breast and bladder human tumor biopsies

1 reference

12 December 2020

Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation

1 reference

12 December 2020

Identifiers

DOI

10.1186/1747-1028-5-13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20478024%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

0 references

1 reference

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2 February 2020

PubMed publication ID

20478024

1 reference