Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. (Q33877362)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24960204%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice (English)

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21 March 2020

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1

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21 March 2020

Joao F Passos

3

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21 March 2020

Laura C Greaves

6

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21 March 2020

Gabriele Saretzki

7

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21 March 2020

Graeme Hewitt

11

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21 March 2020

Glyn Nelson

14

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21 March 2020

Thomas von Zglinicki

18

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Clara Correia-Melo

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21 March 2020

author name string

Caroline Wilson

2

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21 March 2020

Fiona Oakley

4

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21 March 2020

Chris Fox

8

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21 March 2020

Conor Lawless

9

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21 March 2020

Rhys Anderson

10

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21 March 2020

Sylvia Lf Pender

12

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21 March 2020

Nicola Fullard

13

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21 March 2020

Jelena Mann

15

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21 March 2020

Bart van de Sluis

16

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21 March 2020

Derek A Mann

17

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21 March 2020

language of work or name

English

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publication date

24 June 2014

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21 March 2020

published in

Nature Communications

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volume

2

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21 March 2020

page(s)

4172

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Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

24 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Male mice retain a metabolic memory of improved glucose tolerance induced during adult onset, short-term dietary restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Cellular senescence and its effector programs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Telomerase directly regulates NF-κB-dependent transcription.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

NF-κB inhibition delays DNA damage-induced senescence and aging in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

A senescent cell bystander effect: senescence-induced senescence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Role of telomeres and telomerase in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Gross energy metabolism in mice under late onset, short term caloric restriction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Fat maintenance is a predictor of the murine lifespan response to dietary restriction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Telomere dysfunction induces metabolic and mitochondrial compromise.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Inflammatory networks during cellular senescence: causes and consequences

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Feedback between p21 and reactive oxygen production is necessary for cell senescence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

DNA damage foci in mitosis are devoid of 53BP1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Group III secreted phospholipase A2 transgenic mice spontaneously develop inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Telomerase reverse transcriptase delays aging in cancer-resistant mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Molecular inflammation: underpinnings of aging and age-related diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Genetic determinants of human health span and life span: progress and new opportunities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Anti-inflammatory drugs in the 21st century

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Preferential Accumulation of Single-Stranded Regions in Telomeres of Human Fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090717

Motif module map reveals enforcement of aging by continual NF-kappaB activity

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5172

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1 reference

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1 reference

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1 reference

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1 reference

12 December 2020

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1 reference

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1 reference

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1 reference

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Identifiers

DOI

10.1038/NCOMMS5172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24960204%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 March 2020

0 references

1 reference

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21 March 2020

PubMed publication ID

24960204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24960204%20AND%20SRC:MED&resulttype=core&format=json